Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | ATP4A | P20648 | 1/20 | 0.31 |
| ▸ | ATP4B | P51164 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2771532 | 0.78 | RAB9A (0.38) | LMNANPC1MAPTRAB9A | |
| SCHEMBL1000856 | 0.77 | ALDH1A1 (0.44) | LMNAATP4AATP4BMEN1NPC1 | |
| Hydrochloric Acid SCHEMBL11102564 | 0.76 | ALDH1A1 (0.46) | LMNAATP4AATP4BMEN1NPC1 | |
| SCHEMBL29350255 | 0.74 | MAPT (0.33) | ALOX5CYP1A2MEN1NPC1ALDH1A1 | |
| SCHEMBL6172805 | 0.73 | L3MBTL1 (0.56) | LMNAMEN1NPC1ALDH1A1MAPT | |
| SCHEMBL11581850 | 0.72 | CYP3A4 (0.34) | ALOX5LMNACYP1A2ATP4AATP4B | |
| SCHEMBL9390432 | 0.70 | ALOX5 (0.54) | ALOX5NPC1MAPTRAB9A | |
| SCHEMBL6641922 | 0.70 | SMN1; SMN2 (0.37) | LMNAMEN1NPC1MAPTRAB9A | |
| SCHEMBL2642412 | 0.69 | — | — | |
| SCHEMBL9555571 | 0.68 | LMNA (0.51) | LMNAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1816128-A1 | CARBOXYLIC ACID DERIVATIVE CONTAINING THIAZOLE RING AND PHARMACEUTICAL USE THEREOF | Mitsubishi Pharma Corporation (JP) | 2007-08-08 | — | — | EP | disclosed |