Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | PLAU | P00749 | 2/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | F12 | P00748 | 1/20 | 0.41 |
| ▸ | NCF1 | P14598 | 1/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7474495 | 0.75 | AR (0.39) | KDM4ENPC1RAB9AL3MBTL1GPR55 | |
| SCHEMBL244548 | 0.75 | NOS3 (0.41) | NOS3NOS1NOS2 | |
| SCHEMBL199273 | 0.74 | PLAU (0.60) | KDM4ENPC1RAB9AL3MBTL1GPR55 | |
| SCHEMBL29923403 | 0.74 | PLAU (0.60) | KDM4ENPC1RAB9AL3MBTL1GPR55 | |
| SCHEMBL5567669 | 0.74 | KDM4E (0.36) | KDM4ENPC1RAB9AMAPTKMT2A | |
| SCHEMBL6256201 | 0.73 | MAPT (0.44) | KDM4ENPC1RAB9AL3MBTL1MAPT | |
| SCHEMBL30522769 | 0.72 | PLAU (0.58) | KDM4ENPC1RAB9AL3MBTL1GPR55 | |
| SCHEMBL3028469 | 0.72 | BRD4 (0.40) | KDM4EMAPTKMT2AALDH1A1HPGD | |
| SCHEMBL646759 | 0.71 | KDM4E (0.45) | KDM4ENPC1RAB9AL3MBTL1MAPT | |
| SCHEMBL12223316 | 0.70 | PLAU (0.56) | KDM4ENPC1RAB9AL3MBTL1GPR55 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10155725-B2 | Anthelmintic compounds and compositions and method of using thereof | MERIAL, INC. (US) | 2018-12-18 | — | — | US | claimed |
| US-20010044461-A1 | Novel N-aminoalkyldibenzothiopencarboxamide receptor subtype specific ligands | YUAN JUN (US) | 2001-11-22 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10155725-B2 | Anthelmintic compounds and compositions and method of using thereof | CYP3A5, ABCC5, CXXC5 | KDM4E 326/4885NPC1 2184/4885RAB9A 3493/4885 |
| US-20010044461-A1 | Novel N-aminoalkyldibenzothiopencarboxamide receptor subtype specific ligands | CNR1, GLRA1, SIGMAR1 | KDM4E 4589/4885NPC1 862/4885RAB9A 2100/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.