Buloxibutid

Buloxibutid

SCHEMBL557591

CCCCOC(=O)NS(=O)(=O)c1sc(CC(C)C)cc1-c1ccc(Cn2ccnc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
AGTR2 P50052 20/20 1.00
AGTR1 P30556 1/20 1.00
CYP2C9 P11712 1/20 0.84
CYP2B6 P20813 1/20 0.84

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Buloxibutid SCHEMBL30718088 0.99 AGTR2 (0.98) AGTR2AGTR1CYP2C9CYP2B6
Buloxibutid SCHEMBL26934181 0.99 AGTR2 (0.98) AGTR2AGTR1CYP2C9CYP2B6
SCHEMBL557741 0.92 AGTR2 (1.00) AGTR2AGTR1CYP2C9CYP2B6
SCHEMBL1718514 0.92 AGTR2 (1.00) AGTR2AGTR1CYP2C9CYP2B6
SCHEMBL557104 0.91 AGTR2 (1.00) AGTR2AGTR1CYP2C9CYP2B6
SCHEMBL557333 0.91 AGTR2 (1.00) AGTR2AGTR1CYP2C9CYP2B6
SCHEMBL26130429 0.91 AGTR2 (0.83) AGTR2AGTR1CYP2C9CYP2B6
SCHEMBL557456 0.90 AGTR2 (1.00) AGTR2AGTR1CYP2C9CYP2B6
SCHEMBL5214238 0.90 AGTR2 (0.94) AGTR2AGTR1CYP2C9CYP2B6
SCHEMBL26127375 0.90 AGTR2 (0.82) AGTR2AGTR1CYP2C9CYP2B6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 232 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260069572-A1 TREATMENT OF IDIOPATHIC PULMONARY FIBROSIS VICORE PHARMA AB (SE) 2026-03-12 US claimed
US-20260007608-A1 NEW DELAYED RELEASE COMPOSITION FOR PERORAL ADMINISTRATION VICORE PHARMA AB (SE) 2026-01-08 US claimed
US-20250235408-A1 NEW DELAYED RELEASE COMPOSITION FOR PERORAL ADMINISTRATION VICORE PHARMA AB (SE) 2025-07-24 US claimed
US-20250177355-A1 TREATMENT OF IDIOPATHIC PULMONARY FIBROSIS VICORE PHARMA AB (SE) 2025-06-05 US claimed
US-12213961-B2 Treatment of idiopathic pulmonary fibrosis VICORE PHARMA AB (SE) 2025-02-04 US claimed
CN-119300823-A Use of cloth Luo Tide for treating idiopathic pulmonary fibrosis 维科尔药物公司 2025-01-10 CN claimed
EP-4475843-A1 USE OF BULOXIBUTID FOR THE TREATMENT OF IDIOPATHIC PULMONARY FIBROSIS Vicore Pharma AB (SE) 2024-12-18 EP claimed
US-12128029-B2 Treatment of idiopathic pulmonary fibrosis VICORE PHARMA AB (SE) 2024-10-29 US claimed
US-12121614-B2 Delayed release composition for peroral administration VICORE PHARMA AB (SE) 2024-10-22 US claimed
US-20240269081-A1 NEW DRY POWDER COMPOSITION FOR PERORAL ADMINISTRATION VICORE PHARMA AB (SE) 2024-08-15 US claimed
EP-3229839-A1 NEW METHODS AND USES Vicore Pharma AB (SE) 2017-10-18 EP claimed
US-20170266164-A1 NEW METHODS AND USES NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2017-09-21 US claimed
WO-2016092329-A1 NEW METHODS AND USES VICORE PHARMA AB (SE) 2016-06-16 WO claimed
US-8835471-B2 Use of angiotensin II agonists VICORE PHARMA AB 2014-09-16 US claimed
US-20120035232-A1 USE OF ANGIOTENSIN II AGONISTS VICORE PHARMA AB 2012-02-09 US claimed
CN-1529697-B Tricyclic compounds useful as angiotensin II agonists VICORE PHARMA AB 2010-09-22 CN claimed
US-7652054-B2 Tricyclic compounds useful as angiotensin II agonists VICORE PHARMA AB (SE) 2010-01-26 US claimed
US-20090326026-A1 Tricyclic Compounds Useful as Angiotensin II Agonists VICORE PHARMA AB 2009-12-31 US claimed
EP-1395566-B1 TRICYCLIC COMPOUNDS USEFUL AS ANGIOTENSIN II AGONISTS VICORE PHARMA AB (SE) 2007-09-12 EP claimed
US-20040167176-A1 Tricyclic compounds useful as angiotensin II agonists VICORE PHARMA AB (SE) 2004-08-26 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040167176-A1 Tricyclic compounds useful as angiotensin II agonists AGTR1, AGTR2, NPY2R AGTR2 2/4885AGTR1 1/4885CYP2C9 1541/4885
US-20090326026-A1 Tricyclic Compounds Useful as Angiotensin II Agonists AGTR2, AGTR1, NPY4R AGTR2 1/4885AGTR1 2/4885CYP2C9 1155/4885
US-20260069572-A1 TREATMENT OF IDIOPATHIC PULMONARY FIBROSIS MMP1, CFTR, SLC9A1 AGTR2 302/4885AGTR1 458/4885CYP2C9 2687/4885
US-20120035232-A1 USE OF ANGIOTENSIN II AGONISTS AGTR1, AGTR2, REN AGTR2 2/4885AGTR1 1/4885CYP2C9 2062/4885
US-20260007608-A1 NEW DELAYED RELEASE COMPOSITION FOR PERORAL ADMINISTRATION TNNT2, TPMT, TNNC1 AGTR2 438/4885AGTR1 398/4885CYP2C9 807/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.