Ribose (Furanose)

Ribose (Furanose)

SCHEMBL5576201

Nc1ncnc2n[nH]c(I)c12.OC[C@H]1OC(O)[C@H](O)[C@@H]1O

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADK P55263 7/20 0.49
DOT1L Q8TEK3 4/20 0.49
CDK5 Q00535 2/20 0.49
CDK1 P06493 2/20 0.49
CDK2 P24941 2/20 0.49
DCLK1 O15075 1/20 0.49
DAPK3 O43293 1/20 0.49
DYRK3 O43781 1/20 0.49
ROS1 P08922 1/20 0.49
RPS6KB1 P23443 1/20 0.49
FLT3 P36888 1/20 0.49
CSNK1A1 P48729 1/20 0.49
CSNK1D P48730 1/20 0.49
CLK2 P49760 1/20 0.49
IRAK1 P51617 1/20 0.49
DYRK1A Q13627 1/20 0.49
MELK Q14680 1/20 0.49
NTRK3 Q16288 1/20 0.49
HIPK4 Q8NE63 1/20 0.49
SLK Q9H2G2 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ribose (Furanose) SCHEMBL4077631 1.00 ADK (0.49) ADKDOT1LCDK5CDK1CDK2
Ribose (Furanose) SCHEMBL5576202 0.82 ADK (0.52) ADKDOT1LCDK5CDK1CDK2
Ribose (Furanose) SCHEMBL4077632 0.82 ADK (0.52) ADKDOT1LCDK5CDK1CDK2
SCHEMBL3420175 0.78 PIK3CD (0.59) DYRK3CSNK1DMEN1KMT2API4KB
Ribose (Furanose) SCHEMBL4083364 0.76 HIF1A (0.47) ADKDOT1LCDK5CDK1CDK2
Adenine SCHEMBL7746165 0.74 PI4KA (0.58) ADKDOT1LCDK5CDK1CDK2
Ribose (Furanose) SCHEMBL4079014 0.74 PI4KA (0.58) ADKDOT1LCDK5CDK1CDK2
Ribose (Furanose) SCHEMBL4085700 0.74 PI4KA (0.58) ADKDOT1LCDK5CDK1CDK2
Adenine SCHEMBL38386 0.74 PI4KA (0.58) ADKDOT1LCDK5CDK1CDK2
Adenine SCHEMBL7624128 0.74 PI4KA (0.58) ADKDOT1LCDK5CDK1CDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7291463-B2 Incubating/condensating pseudoisocytidine molecule with (1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride to provide a pseudouridine molecule; oncology diagnosis AFFYMETRIX, INC. (US) 2007-11-06 US disclosed