Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 7/20 | 0.49 |
| ▸ | DOT1L | Q8TEK3 | 4/20 | 0.49 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.49 |
| ▸ | CDK1 | P06493 | 2/20 | 0.49 |
| ▸ | CDK2 | P24941 | 2/20 | 0.49 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.49 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.49 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.49 |
| ▸ | ROS1 | P08922 | 1/20 | 0.49 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.49 |
| ▸ | FLT3 | P36888 | 1/20 | 0.49 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.49 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.49 |
| ▸ | CLK2 | P49760 | 1/20 | 0.49 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.49 |
| ▸ | MELK | Q14680 | 1/20 | 0.49 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.49 |
| ▸ | HIPK4 | Q8NE63 | 1/20 | 0.49 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ribose (Furanose) SCHEMBL5576201 | 1.00 | ADK (0.49) | ADKDOT1LCDK5CDK1CDK2 | |
| Ribose (Furanose) SCHEMBL5576202 | 0.82 | ADK (0.52) | ADKDOT1LCDK5CDK1CDK2 | |
| Ribose (Furanose) SCHEMBL4077632 | 0.82 | ADK (0.52) | ADKDOT1LCDK5CDK1CDK2 | |
| SCHEMBL3420175 | 0.78 | PIK3CD (0.59) | DYRK3CSNK1DMEN1KMT2API4KB | |
| Ribose (Furanose) SCHEMBL4083364 | 0.76 | HIF1A (0.47) | ADKDOT1LCDK5CDK1CDK2 | |
| Adenine SCHEMBL7746165 | 0.74 | PI4KA (0.58) | ADKDOT1LCDK5CDK1CDK2 | |
| Ribose (Furanose) SCHEMBL4079014 | 0.74 | PI4KA (0.58) | ADKDOT1LCDK5CDK1CDK2 | |
| Ribose (Furanose) SCHEMBL4085700 | 0.74 | PI4KA (0.58) | ADKDOT1LCDK5CDK1CDK2 | |
| Adenine SCHEMBL38386 | 0.74 | PI4KA (0.58) | ADKDOT1LCDK5CDK1CDK2 | |
| Adenine SCHEMBL7624128 | 0.74 | PI4KA (0.58) | ADKDOT1LCDK5CDK1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7491818-B2 | Nucleic acid labeling compounds | AFFYMETRIX, INC. (US) | 2009-02-17 | — | — | US | disclosed |
| US-7179905-B2 | Nucleic acid labeling compounds | AFFYMETRIX, INC. (US) | 2007-02-20 | — | — | US | disclosed |
| US-6965020-B2 | Nucleic acid labeling compounds | AFFYMETRIX, INC. (US) | 2005-11-15 | — | — | US | disclosed |
| US-20050164268-A1 | Nucleic acid labeling compounds | AFFYMETRIX, INC. | 2005-07-28 | — | — | US | disclosed |
| US-6844433-B2 | Nucleic acid labeling compounds | AFFYMETRIX, INC. (US) | 2005-01-18 | — | — | US | disclosed |
| US-20040210045-A1 | Nucleic acid labeling compounds | MCGALL GLENN (US) | 2004-10-21 | — | — | US | disclosed |
| US-20040002595-A1 | Nucleic acid labeling compounds | AFFYMETRIX, INC. | 2004-01-01 | — | — | US | disclosed |
| US-20030232979-A1 | Nucleic acid labeling compounds | AFFYMETRIX, INC. | 2003-12-18 | — | — | US | disclosed |
| US-6596856-B2 | For probes, comprising a heterocycle condensed with a cyclic group such as ribofuranose derivative; biotin and 5-carboxyfluorescein derivatives | AFFYMETRIX, INC. | 2003-07-22 | — | — | US | disclosed |
| US-20020165372-A1 | Nucleic acid labeling compounds | AFFYMETRIX, INC. | 2002-11-07 | — | — | US | disclosed |
| US-20010044531-A1 | Nucleic acid labeling compounds | AFFYMETRIX, INC. | 2001-11-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040002595-A1 | Nucleic acid labeling compounds | RNGTT, DUT, FBL | ADK 454/4885DOT1L 955/4885CDK5 797/4885 |
| US-20050164268-A1 | Nucleic acid labeling compounds | RNGTT, DUT, FBL | ADK 454/4885DOT1L 955/4885CDK5 797/4885 |
| US-20010044531-A1 | Nucleic acid labeling compounds | RNGTT, DUT, FBL | ADK 454/4885DOT1L 955/4885CDK5 797/4885 |
| US-20020165372-A1 | Nucleic acid labeling compounds | RNGTT, DUT, FBL | ADK 454/4885DOT1L 955/4885CDK5 797/4885 |
| US-20030232979-A1 | Nucleic acid labeling compounds | RNGTT, DUT, FBL | ADK 454/4885DOT1L 955/4885CDK5 797/4885 |
| US-20040210045-A1 | Nucleic acid labeling compounds | RNGTT, DUT, FBL | ADK 454/4885DOT1L 955/4885CDK5 797/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.