Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 9/20 | 0.52 |
| ▸ | DOT1L | Q8TEK3 | 3/20 | 0.52 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.52 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.52 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.52 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.52 |
| ▸ | CDK1 | P06493 | 1/20 | 0.52 |
| ▸ | ROS1 | P08922 | 1/20 | 0.52 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.52 |
| ▸ | CDK2 | P24941 | 1/20 | 0.52 |
| ▸ | FLT3 | P36888 | 1/20 | 0.52 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.52 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.52 |
| ▸ | CLK2 | P49760 | 1/20 | 0.52 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.52 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.52 |
| ▸ | MELK | Q14680 | 1/20 | 0.52 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.52 |
| ▸ | HIPK4 | Q8NE63 | 1/20 | 0.52 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ribose (Furanose) SCHEMBL4077632 | 1.00 | ADK (0.52) | ADKDOT1LCDK5DCLK1DAPK3 | |
| Ribose (Furanose) SCHEMBL5576201 | 0.82 | ADK (0.49) | ADKDOT1LCDK5DCLK1DAPK3 | |
| Ribose (Furanose) SCHEMBL4077631 | 0.82 | ADK (0.49) | ADKDOT1LCDK5DCLK1DAPK3 | |
| SCHEMBL8801 | 0.78 | PIK3CD (0.42) | DYRK3CSNK1DMEN1PI4KAKMT2A | |
| Ribose (Furanose) SCHEMBL4079014 | 0.74 | PI4KA (0.58) | ADKDOT1LCDK5DCLK1DAPK3 | |
| Ribose (Furanose) SCHEMBL4085700 | 0.74 | PI4KA (0.58) | ADKDOT1LCDK5DCLK1DAPK3 | |
| Ribose (Furanose) SCHEMBL8324675 | 0.74 | ADA (0.41) | ADKDOT1LCDK1ALDH1A1HIF1A | |
| SCHEMBL638909 | 0.74 | UMPS (0.39) | ADKDOT1LCDK5DCLK1DAPK3 | |
| Adenine SCHEMBL14636444 | 0.73 | HIF1A (0.49) | ADKDOT1LHIF1ADPP4MEN1 | |
| Ribose (Furanose) SCHEMBL4083364 | 0.71 | HIF1A (0.47) | ADKDOT1LCDK5DCLK1DAPK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291463-B2 | Incubating/condensating pseudoisocytidine molecule with (1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride to provide a pseudouridine molecule; oncology diagnosis | AFFYMETRIX, INC. (US) | 2007-11-06 | — | — | US | disclosed |
| EP-1589025-A2 | Nucleic acid labeling compounds | Affymetrix, Inc. (US) | 2005-10-26 | — | — | EP | disclosed |
| EP-1124838-B1 | NUCLEIC ACID LABELING COMPOUNDS | AFFYMETRIX INC (US) | 2005-06-01 | — | — | EP | disclosed |
| US-6864059-B2 | Biotin containing C-glycoside nucleic acid labeling compounds | AFFYMETRIX, INC. (US) | 2005-03-08 | — | — | US | disclosed |
| US-20030180757-A1 | Nucleic acid labeling compounds | AFFYMETRIX, INC. | 2003-09-25 | — | — | US | disclosed |
| US-20010018514-A1 | NUCLEIC ACID LABELING COMPOUNDS | AFFYMETRIX, INC. | 2001-08-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030180757-A1 | Nucleic acid labeling compounds | RNGTT, DUT, FBL | ADK 454/4885DOT1L 955/4885CDK5 797/4885 |
| US-20010018514-A1 | NUCLEIC ACID LABELING COMPOUNDS | RNGTT, DUT, FBL | ADK 454/4885DOT1L 955/4885CDK5 797/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.