Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A known ✓ | P04350 | 1/20 | 0.30 |
| ▸ | TUBB known ✓ | P07437 | 1/20 | 0.30 |
| ▸ | TUBA3C known ✓ | P0DPH7 | 1/20 | 0.30 |
| ▸ | TUBA1B known ✓ | P68363 | 1/20 | 0.30 |
| ▸ | TUBA4A known ✓ | P68366 | 1/20 | 0.30 |
| ▸ | TUBB4B known ✓ | P68371 | 1/20 | 0.30 |
| ▸ | TUBB3 known ✓ | Q13509 | 1/20 | 0.30 |
| ▸ | TUBB2A known ✓ | Q13885 | 1/20 | 0.30 |
| ▸ | TUBB8 known ✓ | Q3ZCM7 | 1/20 | 0.30 |
| ▸ | TUBA3E known ✓ | Q6PEY2 | 1/20 | 0.30 |
| ▸ | TUBA1A known ✓ | Q71U36 | 1/20 | 0.30 |
| ▸ | TUBA1C known ✓ | Q9BQE3 | 1/20 | 0.30 |
| ▸ | TUBB6 known ✓ | Q9BUF5 | 1/20 | 0.30 |
| ▸ | TUBB2B known ✓ | Q9BVA1 | 1/20 | 0.30 |
| ▸ | TUBB1 known ✓ | Q9H4B7 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16504635 | 0.81 | LMNA (0.46) | MAPTPOLBPKMKMT2ALMNA | |
| SCHEMBL9619081 | 0.79 | MAPT (0.37) | MAPTPOLBPKMKMT2ALMNA | |
| SCHEMBL5576286 | 0.76 | ELANE (0.47) | MAPTPOLBPKMKMT2ALMNA | |
| SCHEMBL246655 | 0.75 | ELANE (0.56) | MAPTPOLBPKMKMT2ALMNA | |
| SCHEMBL27768540 | 0.74 | LMNA (0.61) | MAPTKMT2ALMNAELANE | |
| SCHEMBL28914529 | 0.74 | GSK3B (0.48) | MAPTKMT2ALMNAMEN1CYP3A4 | |
| SCHEMBL215942 | 0.74 | ELANE (0.44) | MAPTKMT2ALMNAMEN1KDM4E | |
| SCHEMBL3120830 | 0.74 | GSK3B (0.48) | MAPTKMT2ALMNAMEN1CYP3A4 | |
| SCHEMBL7457988 | 0.74 | ELANE (0.44) | MAPTKMT2ALMNAMEN1KDM4E | |
| SCHEMBL9619082 | 0.74 | MAPT (0.40) | MAPTPOLBPKMKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7252883-B2 | Coated particles | SEKISUI CHEMICAL CO., LTD. (JP) | 2007-08-07 | — | — | US | disclosed |
| US-20040109995-A1 | Coated particles | SEKISUI CHEMICAL CO., LTD. (JP) | 2004-06-10 | — | — | US | disclosed |