Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | BDKRB1 | P46663 | 2/20 | 0.38 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5583440 | 0.81 | MAPT (0.51) | HCAR3KDM4EGLAALDH1A1MAPT | |
| SCHEMBL5583406 | 0.78 | VCAM1 (0.46) | ALDH1A1MAPTMAPK1SMN1; SMN2NPC1 | |
| SCHEMBL5583455 | 0.76 | HCAR3 (0.41) | HCAR3KDM4EGLAALDH1A1MAPT | |
| SCHEMBL2188552 | 0.76 | ALDH1A1 (0.49) | KDM4EALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL12419055 | 0.74 | ALDH1A1 (0.39) | KDM4EALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL5583508 | 0.74 | HCAR3 (0.43) | HCAR3KDM4EGLAALDH1A1MAPT | |
| SCHEMBL8045736 | 0.74 | HCAR3 (0.43) | HCAR3KDM4EGLAALDH1A1MAPT | |
| SCHEMBL5583438 | 0.74 | CYP1A2 (0.56) | ALDH1A1MAPTMAPK1L3MBTL1KMT2A | |
| SCHEMBL31633570 | 0.74 | CYP1A2 (0.56) | ALDH1A1MAPTMAPK1L3MBTL1KMT2A | |
| SCHEMBL8744236 | 0.74 | CRHBP (0.52) | ALDH1A1MAPTMAPK1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7301049-B2 | Photolabile esters and their uses | THE INSTITUTE OF CANCER RESEARCH (GB) | 2007-11-27 | — | — | US | disclosed |
| US-20040242653-A1 | Photolabile esters and their uses | THE INSTITUTE OF CANCER RESEARCH (GB) | 2004-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040242653-A1 | Photolabile esters and their uses | DIMT1, DCTD, DTYMK | HCAR3 3671/4885KDM4E 853/4885GLA 1697/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.