SCHEMBL5583698

SCHEMBL5583698

FC(F)(F)c1c[c]ccc1Oc1ccccc1

nearest known ligand 0.37

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
AR P10275 9/20 0.37
LTA4H P09960 2/20 0.37
PTGS2 P35354 1/20 0.37
TSHR P16473 1/20 0.37
STK39 Q9UEW8 1/20 0.35
RIPK1 Q13546 1/20 0.34
RAB9A P51151 1/20 0.34
RAF1 P04049 1/20 0.34
MAPT P10636 1/20 0.33
LMNA P02545 1/20 0.33
GAA P10253 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9685472 0.86 AR (0.37) ARLTA4HPTGS2TSHRRIPK1
SCHEMBL5583620 0.85 L3MBTL1 (0.39) LTA4HPTGS2RAB9AMAPTLMNA
SCHEMBL5583758 0.83 AR (0.47) ARMAPTKMT2A
SCHEMBL27488193 0.83 RIPK1 (0.41) LTA4HTSHRRIPK1RAF1LMNA
SCHEMBL919536 0.79 LTA4H (0.48) ARLTA4HPTGS2
SCHEMBL4008636 0.78 LTA4H (0.42) ARLTA4HPTGS2
SCHEMBL1676646 0.77 LTA4H (0.53) ARLTA4HPTGS2TSHRRIPK1
SCHEMBL1451604 0.77 LTA4H (0.46) LTA4HTSHRRIPK1LMNAGAA
SCHEMBL921134 0.77 LTA4H (0.41) LTA4HTSHRRIPK1LMNAGAA
SCHEMBL1069020 0.76 HSD11B1 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7183278-B1 Picolinamide derivative and harmful organism control agent comprising said picolinamide derivative as active component MEIJI SEIKA KAISHA, LTD. (JP) 2007-02-27 US claimed
US-20060235192-A1 Soluble, low dielectrical constant, unsymmetrical polyimide and a method for preparing the same CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY CHINESE ACADEMY OF SCIENCE (CN) 2006-10-19 US claimed
CN-1273517-C Soluble asymmetric polyimide and preparation method thereof CHANGCHUN APPLIED CHEMISTRY (CN) 2006-09-06 CN claimed
CN-1687188-A Soluble asymmetric polyimide and preparation method thereof CHANGCHUN APPLIED CHEMISTRY (CN) 2005-10-26 CN claimed
EP-1134214-A1 PICOLINAMIDE DERIVATIVES AND PEST CONTROLLERS CONTAINING THE SAME AS THE ACTIVE INGREDIENT MEIJI SEIKA KAISHA LTD. (JP) 2001-09-19 EP claimed
US-7183278-B1 Picolinamide derivative and harmful organism control agent comprising said picolinamide derivative as active component MEIJI SEIKA KAISHA, LTD. (JP) 2007-02-27 US disclosed
US-20060235192-A1 Soluble, low dielectrical constant, unsymmetrical polyimide and a method for preparing the same CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY CHINESE ACADEMY OF SCIENCE (CN) 2006-10-19 US disclosed
CN-1273517-C Soluble asymmetric polyimide and preparation method thereof CHANGCHUN APPLIED CHEMISTRY (CN) 2006-09-06 CN disclosed
CN-1687188-A Soluble asymmetric polyimide and preparation method thereof CHANGCHUN APPLIED CHEMISTRY (CN) 2005-10-26 CN disclosed
EP-1134214-A1 PICOLINAMIDE DERIVATIVES AND PEST CONTROLLERS CONTAINING THE SAME AS THE ACTIVE INGREDIENT MEIJI SEIKA KAISHA LTD. (JP) 2001-09-19 EP disclosed
US-6048991-A Preparation of epoxides BASF AKTIENGESELLSCHAFT (DE) 2000-04-11 US disclosed
US-5916430-A Preparation of epoxides BASF AKTIENGESELLSCHAFT (DE) 1999-06-29 US disclosed
US-5179210-A PREPARATION OF N-SUBSTITUTED IMIDAZOLES BASF AKTIENGESELLSCHAFT (DE) 1993-01-12 US disclosed
US-5159117-A Reacting ketone or aldehyde with nitrites in presence of acid catalyst BASF AKTIENGESELLSCHAFT (DE) 1992-10-27 US disclosed
US-5117004-A Carboxylation with carbon dioxide BASF AKTIENGESELLSCHAFT (DE) 1992-05-26 US disclosed
EP-0485783-A2 Process for producing epoxy compounds BASF Aktiengesellschaft (DE) 1992-05-20 EP disclosed
EP-0472118-A1 Process for production of alpha,alpha-dialkoxycetones BASF Aktiengesellschaft (DE) 1992-02-26 EP disclosed
EP-0460451-A1 Process for the preparation of alpha-hydroxymethyl-ketals BASF Aktiengesellschaft (DE) 1991-12-11 EP disclosed
EP-0457139-A2 Process for the preparation of N-substituted imidazoles BASF Aktiengesellschaft (DE) 1991-11-21 EP disclosed
EP-0328955-A2 Process for the preparation of imidazole-2-carboxylic acids BASF Aktiengesellschaft (DE) 1989-08-23 EP disclosed