Chloroform

Chloroform

SCHEMBL558767

ClC(Cl)Cl.O

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO

The experimentally established mechanism targets of Chloroform. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chloroform SCHEMBL10439416 1.00 LMNA (0.80)
Chloroform SCHEMBL1014755 0.91
Chloroform SCHEMBL10949561 0.89 LMNA (1.00)
Chloroform SCHEMBL10950487 0.89 LMNA (1.00)
Chloroform SCHEMBL2084455 0.89
Chloroform SCHEMBL88 0.89
Chloroform SCHEMBL30536988 0.89
Chloroform SCHEMBL28447144 0.84
Chloroform SCHEMBL8631228 0.84
Chloroform SCHEMBL2221141 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 260 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119930924-A Zwitterionic nanogel and application thereof 苏州健雄职业技术学院 2025-05-06 CN claimed
CN-118239857-A Preparation method of iodixanol impurity I 浙江海洲制药股份有限公司 2024-06-25 CN claimed
CN-118164825-A Preparation method of urushiol active alkylphenol 中华全国供销合作总社西安生漆涂料研究所 2024-06-11 CN claimed
CN-118032896-A Lactoferrin biosensor and preparation method and application thereof 湖南省产商品质量检验研究院 2024-05-14 CN claimed
CN-111247097-B Activated carbon and preparation method thereof 关西热化学株式会社 2024-03-05 CN claimed
CN-111500657-B Method for co-producing hypocrellin A and tabasheer exopolysaccharide 杭州巴洛特生物科技有限公司 2023-10-13 CN claimed
CN-114894918-B Rapid extraction and purification method and detection method for acid dye in complex food 宁波海关技术中心 2023-07-04 CN claimed
CN-116068119-A Detection method of kidney-tonifying essence-replenishing oral liquid 九芝堂股份有限公司 2023-05-05 CN claimed
CN-114432294-B 5-nornobiletin and preparation method and application thereof 天津商业大学 2023-04-21 CN claimed
CN-113087643-B Agmatine composite salt and preparation method thereof 武汉远大弘元股份有限公司 2023-03-31 CN claimed
CN-114894918-A Rapid extraction and purification method and detection method for acid dye in complex food 宁波海关技术中心 2022-08-12 CN claimed
CN-113663049-B Li nationality medicine postpartum medicated bath effervescent granules and preparation method thereof 中国热带农业科学院热带作物品种资源研究所 2022-07-05 CN claimed
CN-114685320-A Gaminobutylamine taurate and preparation method and application thereof 武汉远大弘元股份有限公司 2022-07-01 CN claimed
CN-114432294-A 5-demethylnobiletin and preparation method and application thereof 天津商业大学 2022-05-06 CN claimed
CN-114196974-A Electrochemical synthesis method of vanillin 上海应用技术大学 2022-03-18 CN claimed
CN-109610031-B Preparation of biomass carbon-doped nanofiber felt and application of biomass carbon-doped nanofiber felt in separation of oil-water mixture 西北师范大学 2020-12-22 CN claimed
CN-105016989-A Synthetic method of chlorobenzene glyceryl ether BEIJING SUNPU BIOCHEMISTRY TECHNOLOGY CO LTD 2015-11-04 CN claimed
CN-104211667-A Plant extract applied in taxol preparation and preparation method thereof DASHENGXIANG WUHAN TRADITIONAL CHINESE MEDICINE INVEST MAN CO LTD 2014-12-17 CN claimed
CN-101619054-B New coumarin active content, preparation method and application thereof UNIV NORTHEAST FORESTRY 2011-02-16 CN claimed
CN-101143920-A Copolymer and cross linking compound for unsaturated anhydride or unsaturated imide and cyclic lactone UNIV CHONGQING (CN) 2008-03-19 CN claimed