SCHEMBL5587777

SCHEMBL5587777

Cc1cc(O)c(O)c(C(=O)O)c1-c1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCL2L1 Q07817 8/20 0.51
MCL1 Q07820 8/20 0.47
BCL2 P10415 6/20 0.47
ALDH1A1 P00352 1/20 0.46
CYP3A4 P08684 3/20 0.44
MAPT P10636 1/20 0.44
BCL2A1 Q16548 5/20 0.42
ACHE P22303 1/20 0.42
FABP3 P05413 2/20 0.41
FABP4 P15090 2/20 0.41
PRNP P04156 1/20 0.41
PPARG P37231 1/20 0.41
RXFP1 Q9HBX9 1/20 0.41
NR2E3 Q9Y5X4 1/20 0.41
NCOR2 Q9Y618 1/20 0.41
BAK1 Q16611 1/20 0.40
AKR1C2 P52895 1/20 0.40
AKR1C1 Q04828 1/20 0.40
CYP2C9 P11712 1/20 0.40
KMT2A Q03164 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5587936 0.80 FABP4 (0.43) BCL2L1MCL1BCL2ALDH1A1MAPT
SCHEMBL25781920 0.80 LMNA (0.45) BCL2L1MCL1BCL2MAPTBCL2A1
SCHEMBL28288827 0.80 HTT (0.45) BCL2L1MCL1BCL2ALDH1A1CYP3A4
Ethane SCHEMBL18860236 0.78 HTT (0.44) BCL2L1MCL1BCL2MAPTBCL2A1
SCHEMBL26072111 0.78 LMNA (0.44) BCL2L1MCL1BCL2ALDH1A1MAPT
SCHEMBL11586143 0.77 ALDH1A1 (0.47) MCL1ALDH1A1CYP3A4FABP3FABP4
SCHEMBL5589359 0.76 PTPN1 (0.49) BCL2L1MCL1PPARGBAK1
SCHEMBL14760848 0.75 MAPT (0.53) BCL2L1MCL1ALDH1A1CYP3A4MAPT
SCHEMBL5589911 0.75 LDHA (0.45) ALDH1A1CYP3A4MAPTFABP3FABP4
SCHEMBL6026916 0.75 FABP4 (0.43) MCL1ALDH1A1CYP3A4MAPTACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7247687-B2 Late transition metal catalysts for olefin polymerization and oligomerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-07-24 US disclosed
EP-1521758-B1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION EXXONMOBIL CHEM PATENTS INC (US) 2006-05-24 EP disclosed
US-20060047094-A1 Late transition metal catalysts for olefin polymerization and oligomerization EXXONMOBIL CHEMICAL PATENTS INC. 2006-03-02 US disclosed
EP-1521758-A1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION Exxonmobil Chemical Patents Inc. (US) 2005-04-13 EP disclosed
WO-2004007509-A1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2004-01-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060047094-A1 Late transition metal catalysts for olefin polymerization and oligomerization MLX, LOX, LMTK3 BCL2L1 3763/4885MCL1 1660/4885BCL2 4663/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.