Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 1/20 | 0.53 |
| ▸ | EP300 | Q09472 | 2/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.45 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL678077 | 0.83 | ALOX5 (0.56) | OPRD1EP300TRPV1RAB9ASMN1; SMN2 | |
| SCHEMBL7760695 | 0.81 | OPRD1 (0.56) | OPRD1EP300MAPTMEN1KMT2A | |
| SCHEMBL7902764 | 0.80 | OPRD1 (0.54) | OPRD1EP300MAPTCYP1A2CYP2D6 | |
| SCHEMBL14195275 | 0.79 | ALOX5 (0.51) | OPRD1EP300MAPK14 | |
| SCHEMBL7756777 | 0.78 | OPRD1 (0.52) | OPRD1EP300CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL7899189 | 0.77 | OPRD1 (0.51) | OPRD1EP300MAPTMEN1TSHR | |
| SCHEMBL7760704 | 0.75 | OPRD1 (0.49) | OPRD1EP300MAPTMEN1TSHR | |
| SCHEMBL7760707 | 0.75 | OPRD1 (0.50) | OPRD1EP300MEN1KMT2AL3MBTL1 | |
| SCHEMBL7760717 | 0.75 | OPRD1 (0.50) | OPRD1EP300MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7761536 | 0.74 | OPRD1 (0.48) | OPRD1EP300MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1799196-A2 | CONTROLLED RELEASE PHARMACEUTICAL COMPOSITIONS COMPRISING A FUMARIC ACID ESTER | Aditech Pharma AB (SE) | 2007-06-27 | — | — | EP | disclosed |
| WO-2006037342-A2 | CONTROLLED RELEASE PHARMACEUTICAL COMPOSITIONS COMPRISING A FUMARIC ACID ESTER | ADITECH PHARMA AB (SE) | 2006-04-13 | — | — | WO | disclosed |