Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 1/20 | 0.50 |
| ▸ | EP300 | Q09472 | 2/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | PRF1 | P14222 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | BCR | P11274 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7760717 | 0.81 | OPRD1 (0.50) | OPRD1EP300PTGS2MEN1KMT2A | |
| SCHEMBL7760695 | 0.80 | OPRD1 (0.56) | OPRD1EP300PTGS2MEN1KMT2A | |
| SCHEMBL7902764 | 0.78 | OPRD1 (0.54) | OPRD1EP300PTGS2L3MBTL1MAPK14 | |
| SCHEMBL7756777 | 0.76 | OPRD1 (0.52) | OPRD1EP300PTGS2L3MBTL1KDM4E | |
| SCHEMBL7899189 | 0.76 | OPRD1 (0.51) | OPRD1EP300MEN1KMT2AL3MBTL1 | |
| SCHEMBL5599629 | 0.75 | OPRD1 (0.53) | OPRD1EP300MEN1KMT2AL3MBTL1 | |
| SCHEMBL678077 | 0.75 | ALOX5 (0.56) | OPRD1EP300PTGS2MAPK14KDM4E | |
| Hydrochloric Acid SCHEMBL8985552 | 0.74 | OPRD1 (0.49) | OPRD1EP300PTGS2MEN1KMT2A | |
| SCHEMBL11520829 | 0.74 | ESR1 (0.59) | OPRD1PTGS2MEN1KMT2AAPP | |
| SCHEMBL7760704 | 0.74 | OPRD1 (0.49) | OPRD1EP300MEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0728755-B1 | Thiophene compounds, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2001-04-11 | — | — | EP | disclosed |
| EP-0728755-A1 | Thiophene compounds, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-08-28 | — | — | EP | disclosed |