SCHEMBL56104

SCHEMBL56104

CC1(C)OB(c2ccc([N+](=O)[O-])cc2)OC1(C)C

nearest known ligand 0.52

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LPL P06858 12/20 0.52
LIPG Q9Y5X9 12/20 0.52
CA1 P00915 3/20 0.47
CA2 P00918 3/20 0.47
CA9 Q16790 3/20 0.47
CA12 O43570 1/20 0.47
CA3 P07451 1/20 0.47
CA4 P22748 1/20 0.47
CA6 P23280 1/20 0.47
CA5A P35218 1/20 0.47
CA7 P43166 1/20 0.47
CA14 Q9ULX7 1/20 0.47
CA5B Q9Y2D0 1/20 0.47
HSD17B10 Q99714 2/20 0.47
ACHE P22303 1/20 0.47
F11 P03951 1/20 0.42
ALDH1A1 P00352 2/20 0.42
RECQL P46063 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17947401 0.90 P4HB (0.51) LPLLIPG
SCHEMBL15481277 0.90 P4HB (0.51) LPLLIPG
SCHEMBL12566977 0.83 MAOB (0.56) LPLLIPGCA1CA2CA9
SCHEMBL20401792 0.83 LMNA (0.42) LPLLIPGCA1CA2CA9
SCHEMBL15981215 0.83 MAOB (0.56) LPLLIPGCA1CA2CA9
SCHEMBL5950108 0.82 P4HB (0.44) LPLLIPGCA1CA2CA9
SCHEMBL21383656 0.82 ALDH1A1 (0.39) LPLLIPGCA1CA2CA9
SCHEMBL228212 0.81 LPL (0.71) LPLLIPGCA1CA2CA9
SCHEMBL1572672 0.81 CYP19A1 (0.45) LPLLIPGCA1CA2CA9
SCHEMBL21383659 0.81 F2 (0.40) LPLLIPGCA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 284 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118406055-A Compound DNNP, preparation method thereof and application thereof in detection of hydrogen sulfide 江苏科技大学 2024-07-30 CN claimed
CN-109851550-A 7- aminocarbazole sulfamide derivative and its preparation method and application 中国医学科学院医药生物技术研究所 2019-06-07 CN claimed
US-20260078117-A1 COMPOUNDS AND METHODS OF USE TANGO THERAPEUTICS INC (US) 2026-03-19 US disclosed
US-20250302815-A1 PROTEIN TYROSINE PHOSPHATASE TARGETING LIGANDS CALICO LIFE SCIENCES LLC 2025-10-02 US disclosed
EP-4561999-A1 TARGETED PROTEIN DEGRADATION OF PARP14 FOR USE IN THERAPY Abbvie Operations Singapore Pte. Ltd. (SG) 2025-06-04 EP disclosed
US-12304907-B2 Compounds and methods of use TANGO THERAPEUTICS, INC. (US) 2025-05-20 US disclosed
US-20250152719-A1 FUSED IMIDE DERIVATIVE CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD. (CN) 2025-05-15 US disclosed
EP-4536639-A1 SUBSTITUTED BIARYL ENDOCHIN-LIKE QUINOLONES WITH ENHANCED ANTIPARASITIC ACTIVITY Oregon Health & Science University (US) 2025-04-16 EP disclosed
US-12264154-B2 Compounds and methods of use TANGO THERAPEUTICS, INC. (US) 2025-04-01 US disclosed
US-20250084081-A1 COMPOUNDS FOR TARGETED DEGRADATION OF BRD9 C4 THERAPEUTICS, INC. (US) 2025-03-13 US disclosed
US-12157735-B2 Compounds for targeted degradation of BRD9 C4 THERAPEUTICS, INC. (US) 2024-12-03 US disclosed
EP-1127060-B8 HYDROBORONATION PROCESS COMMW SCIENT IND RES ORG (AU) 2005-01-05 EP disclosed
US-20040192767-A1 EP4 receptor antagonists ASTERAND UK ACQUISITION LIMITED (GB) 2004-09-30 US disclosed
WO-2004067524-A1 EP4 RECEPTOR ANTAGONISTS PHARMAGENE LABORATORIES LIMITED (GB) 2004-08-12 WO disclosed
US-20040133028-A1 Hydroboronation process COMMONWEALTH SCIENTIFIC 2004-07-08 US disclosed
EP-1127060-B1 HYDROBORONATION PROCESS COMMW SCIENT IND RES ORG (AU) 2004-04-07 EP disclosed
US-6680401-B1 BORON COMPOUNDS SUCH AS 4-(METHOXYMETHYL)-1,3,2-DIOXABOROLANE, USED AS COUPLERS OR CHEMICAL INTERMEDIATES FOR DRUGS, PESTICIDES OR IN COMBINATORIAL CHEMISTRY COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2004-01-20 US disclosed
EP-1127060-A4 HYDROBORONATION PROCESS COMMW SCIENT IND RES ORG (AU) 2002-08-21 EP disclosed
EP-1127060-A1 HYDROBORONATION PROCESS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2001-08-29 EP disclosed
WO-2000027853-A1 HYDROBORONATION PROCESS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2000-05-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040192767-A1 EP4 receptor antagonists PTGER4, PTGER1, NR4A1 LPL 3479/4885LIPG 3796/4885CA1 2799/4885
US-20250302815-A1 PROTEIN TYROSINE PHOSPHATASE TARGETING LIGANDS PTPN1, PTPN2, PTPN18 LPL 293/4885LIPG 204/4885CA1 4658/4885
US-20040133028-A1 Hydroboronation process ALKBH3, HPD, HVCN1 LPL 4659/4885LIPG 4522/4885CA1 2357/4885
US-12157735-B2 Compounds for targeted degradation of BRD9 BRD9, BRD1, BRWD1 LPL 3414/4885LIPG 3588/4885CA1 4765/4885
US-12264154-B2 Compounds and methods of use F12, C1R, ABCG2 LPL 2221/4885LIPG 2618/4885CA1 1719/4885
US-12304907-B2 Compounds and methods of use F12, C1R, ABCG2 LPL 2221/4885LIPG 2618/4885CA1 1719/4885
US-20250084081-A1 COMPOUNDS FOR TARGETED DEGRADATION OF BRD9 BRD9, BRD1, BRWD1 LPL 3414/4885LIPG 3588/4885CA1 4765/4885
US-20260078117-A1 COMPOUNDS AND METHODS OF USE NR3C2, ADRA1A, CNR1 LPL 1131/4885LIPG 1319/4885CA1 701/4885
US-20250152719-A1 FUSED IMIDE DERIVATIVE WEE1, WEE2, CYP4F11 LPL 4103/4885LIPG 3361/4885CA1 3496/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.