Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 1/20 | 0.68 |
| ▸ | HNF4A | P41235 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29350695 | 1.00 | IDH1 (0.68) | IDH1HNF4AGAAMEN1KMT2A | |
| SCHEMBL29860720 | 0.89 | GAA (0.67) | IDH1GAAMEN1KMT2AKDM4E | |
| SCHEMBL564615 | 0.89 | GAA (0.67) | IDH1GAAMEN1KMT2AKDM4E | |
| SCHEMBL29412587 | 0.89 | GAA (0.67) | IDH1GAAMEN1KMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL21173959 | 0.87 | GAA (0.64) | IDH1GAAMEN1KMT2AKDM4E | |
| SCHEMBL564946 | 0.86 | KDM4E (0.53) | IDH1HNF4AGAAMEN1KMT2A | |
| SCHEMBL565060 | 0.86 | ALDH1A1 (0.58) | IDH1HNF4AGAAMEN1KMT2A | |
| SCHEMBL564633 | 0.86 | ESR1 (0.58) | IDH1HNF4AGAAMEN1KMT2A | |
| SCHEMBL565083 | 0.85 | GAA (0.52) | IDH1HNF4AGAAMEN1KMT2A | |
| SCHEMBL564637 | 0.84 | KDM4E (0.80) | IDH1HNF4AGAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0164120-B1 | A METHOD FOR HIGH CONTRAST DEVELOPMENT OF A SILVER HALIDE PHOTOGRAPHIC MATERIAL | FUJI PHOTO FILM CO., LTD. (JP) | 1989-11-15 | — | — | EP | claimed |
| CN-112961891-B | Method for preparing icariin by using biphasic enzymatic reaction | 西安巨子生物基因技术股份有限公司 | 2024-01-26 | — | — | CN | disclosed |
| US-10898516-B2 | Compositions and methods of treating diabetic retinopathy | CASE WESTERN UNIVERSITY (US) | 2021-01-26 | — | — | US | disclosed |
| US-10568851-B2 | Compounds and methods of treating ocular disorders | CASE WESTERN RESERVE UNIVERSITY (US) | 2020-02-25 | — | — | US | disclosed |
| US-10426773-B2 | Systems pharmacology for treating ocular disorders | CASE WESTERN UNIVERSITY (US) | 2019-10-01 | — | — | US | disclosed |
| EP-2509596-B1 | GAMMA AMINOACIDS FOR TREATING OCULAR DISORDERS | UNIV CASE WESTERN RESERVE (US) | 2019-08-28 | — | — | EP | disclosed |
| US-20190255102-A1 | COMPOSITIONS AND METHODS OF TREATING DIABETIC RETINOPATHY | CASE WESTERN UNIVERSITY | 2019-08-22 | — | — | US | disclosed |
| US-10272106-B2 | Compositions and methods of treating diabetic retinopathy | CASE WESTERN RESERVE UNIVERSITY (US) | 2019-04-30 | — | — | US | disclosed |
| US-20190099420-A1 | SYSTEMS PHARMACOLOGY FOR TREATING OCULAR DISORDERS | CASE WESTERN UNIVERSITY | 2019-04-04 | — | — | US | disclosed |
| US-10208049-B2 | Compounds and methods of treating ocular disorders | CASE WESTERN RESERVE UNIVERSITY (US) | 2019-02-19 | — | — | US | disclosed |
| EP-0387725-A2 | Production of thiophene-2,5-dicarboxylic acid diesters and tetrahydrothiophene-2,5-dicarboxylic acid diesters | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1990-09-19 | — | — | EP | disclosed |
| EP-0203521-B1 | A PROCESS FOR PREPARING NEGATIVE IMAGES | FUJI PHOTO FILM CO., LTD. (JP) | 1989-12-13 | — | — | EP | disclosed |
| US-4824764-A | HIGH CONTRAST IMAGES | FUJI PHOTO FILM CO., LTD. (JP) | 1989-04-25 | — | — | US | disclosed |
| US-4740452-A | DIHYDROXYBENZENE-TYPE DEVELOPER, SULFITE PRESERVATIVE, AND AMINE DERIVATIVE | FUJI PHOTO FILM CO., LTD. (JP) | 1988-04-26 | — | — | US | disclosed |
| EP-0203521-A2 | A process for preparing negative images | FUJI PHOTO FILM CO., LTD. (JP) | 1986-12-03 | — | — | EP | disclosed |
| EP-0123902-A2 | Procedure for the determination of peroxidase activity by end dilution titration and means for its realization | Byk-Sangtec Diagnostica GmbH & Co. KG (DE) | 1984-11-07 | — | — | EP | disclosed |
| US-4334005-A | Transition metal photoreduction systems and processes | EASTMAN KODAK COMPANY (US) | 1982-06-08 | — | — | US | disclosed |
| US-4314019-A | NONSILVER PHOTOGRAPHY; COBALT AMMINE COMPLEXES) QUINONE REDUCING AGENTS | EASTMAN KODAK COMPANY (US) | 1982-02-02 | — | — | US | disclosed |
| US-4201588-A | NONSILVER PHOTOGRAPHIC FILMS; DISULFIDE, DIAZOANTHRONE, DIAZOPHENANTHRONE, AROMATIC AZIDE, CARBAZIDES OR QUINONES AS PHOTOREDUCTANT; EXTERNAL HYDROGEN SOURCE | EASTMAN KODAK COMPANY (US) | 1980-05-06 | — | — | US | disclosed |
| US-3985763-A | DYESTUFFS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10426773-B2 | Systems pharmacology for treating ocular disorders | GRK1, MTNR1A, MTNR1B | IDH1 3431/4885HNF4A 1864/4885GAA 496/4885 |
| US-20190255102-A1 | COMPOSITIONS AND METHODS OF TREATING DIABETIC RETINOPATHY | GPR119, ARRB1, GRK1 | IDH1 3818/4885HNF4A 1722/4885GAA 1536/4885 |
| US-10272106-B2 | Compositions and methods of treating diabetic retinopathy | GPR119, ARRB1, GRK1 | IDH1 3818/4885HNF4A 1722/4885GAA 1536/4885 |
| US-20190099420-A1 | SYSTEMS PHARMACOLOGY FOR TREATING OCULAR DISORDERS | GRK1, MTNR1A, MTNR1B | IDH1 3431/4885HNF4A 1864/4885GAA 496/4885 |
| US-10568851-B2 | Compounds and methods of treating ocular disorders | ALDH1A2, TXNRD2, TXNRD1 | IDH1 1937/4885HNF4A 1605/4885GAA 204/4885 |
| US-10208049-B2 | Compounds and methods of treating ocular disorders | ALDH1A2, NR2E3, LRAT | IDH1 2069/4885HNF4A 1200/4885GAA 251/4885 |
| US-10898516-B2 | Compositions and methods of treating diabetic retinopathy | GPR119, ARRB1, GRK1 | IDH1 3818/4885HNF4A 1722/4885GAA 1536/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.