Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.62 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.55 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.55 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.55 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.55 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.55 |
| ▸ | CNR2 | P34972 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28283137 | 0.87 | RAB9A (0.54) | RAB9AHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL2230478 | 0.84 | RAB9A (0.60) | RAB9AHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL25474761 | 0.83 | RAB9A (0.58) | RAB9AHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL30956107 | 0.83 | RAB9A (0.58) | RAB9AHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL13306750 | 0.83 | RAB9A (0.58) | RAB9AHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8617844 | 0.82 | RAB9A (0.55) | RAB9AHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL24898159 | 0.82 | RAB9A (0.66) | RAB9AHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL4097649 | 0.82 | RAB9A (0.61) | RAB9AHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL1207770 | 0.81 | RAB9A (0.68) | RAB9AHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8790412 | 0.81 | RAB9A (0.77) | RAB9AMAPTMEN1TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116444430-A | Off-on near infrared lead ion detection fluorescent probe YSQ and preparation method and application thereof | 江苏科技大学 | 2023-07-18 | — | — | CN | claimed |
| CN-113637004-B | Aluminum ion detection fluorescent probe based on bifunctional small organic molecule as matrix, and preparation method and application thereof | 江苏科技大学 | 2022-09-23 | — | — | CN | claimed |
| CN-114790200-A | Fluorescence-enhanced zinc ion detection fluorescent probe ENO and preparation method and application thereof | 江苏科技大学 | 2022-07-26 | — | — | CN | claimed |
| CN-110590756-B | Phenolphthalein Schiff base fluorescent probe and preparation method and application thereof | 南通大学 | 2022-04-22 | — | — | CN | claimed |
| CN-113307801-B | Phenolphthalein quinoline Al3+Preparation method and application of fluorescent probe | 南通大学 | 2022-04-22 | — | — | CN | claimed |
| CN-113637004-A | Aluminum ion detection fluorescent probe based on dual-functional organic micromolecule as matrix and preparation method and application thereof | 江苏科技大学 | 2021-11-12 | — | — | CN | claimed |
| CN-113307801-A | Phenolphthalein quinoline Al3+Preparation method and application of fluorescent probe | 南通大学 | 2021-08-27 | — | — | CN | claimed |
| CN-110590756-A | Phenolphthalein Schiff base fluorescent probe and preparation method and application thereof | 南通大学 | 2019-12-20 | — | — | CN | claimed |
| CN-116444430-B | Off-on near infrared lead ion detection fluorescent probe YSQ and preparation method and application thereof | 江苏科技大学 | 2026-01-30 | — | — | CN | disclosed |
| CN-118955323-A | Used for Al3+Naphthalene schiff base fluorescent probe for detection, preparation method and application | 西安石油大学 | 2024-11-15 | — | — | CN | disclosed |
| US-12018012-B2 | Aryl cyclopropyl-amino-isoquinolinyl amide compounds | AERIE PHARMACEUTICALS, INC. (US) | 2024-06-25 | — | — | US | disclosed |
| US-11891376-B2 | Aryl cyclopropyl-amino-isoquinolinyl amide compounds | AERIE PHARMACEUTICALS, INC. (US) | 2024-02-06 | — | — | US | disclosed |
| CN-114790200-B | Fluorescence enhancement type zinc ion detection fluorescent probe ENO, and preparation method and application thereof | 江苏科技大学 | 2023-11-24 | — | — | CN | disclosed |
| CN-114790200-B | Fluorescence enhancement type zinc ion detection fluorescent probe ENO, and preparation method and application thereof | 江苏科技大学 | 2023-11-24 | — | — | CN | disclosed |
| EP-1320523-B1 | BRANCHED CHAIN AMINO ACID-DEPENDENT AMINOTRANSFERASE INHIBITORS AND THEIR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES | WARNER LAMBERT CO (US) | 2005-06-22 | — | — | EP | disclosed |
| US-20050004167-A1 | Branched chain amino acid-dependent aminotransferase inhibitors and their use in the treatment of neurodegenerative diseases | WARNER-LAMBERT COMPANY LLC | 2005-01-06 | — | — | US | disclosed |
| US-20040157865-A1 | Naphthol, quinoline and isoquinoline-derived urea modulators of vanilloid VR1 receptor | JANSSEN PHARMACEUTICA, N.V. (BE) | 2004-08-12 | — | — | US | disclosed |
| WO-2004007459-A2 | NAPHTHOL, QUINOLINE AND ISOQUINOLINE-DERIVATIVES AS MODULATORS OF VANILLOID VR1 RECEPTOR | JANSSEN PHARMACEUTICA N.V. (BE) | 2004-01-22 | — | — | WO | disclosed |
| EP-1320523-A2 | BRANCHED CHAIN AMINO ACID-DEPENDENT AMINOTRANSFERASE INHIBITORS AND THEIR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES | Warner-Lambert Company LLC (US) | 2003-06-25 | — | — | EP | disclosed |
| WO-2002024672-A2 | BRANCHED CHAIN AMINO ACID-DEPENDENT AMINOTRANSFERASE INHIBITORS AND THEIR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES | WARNER-LAMBERT COMPANY LLC (US) | 2002-03-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050004167-A1 | Branched chain amino acid-dependent aminotransferase inhibitors and their use in the treatment of neurodegenerative diseases | BCAT1, BCAT2, ABAT | RAB9A 2547/4885HDAC3 2570/4885HDAC4 3534/4885 |
| US-12018012-B2 | Aryl cyclopropyl-amino-isoquinolinyl amide compounds | UACA, HRAS, MYLK | RAB9A 541/4885HDAC3 1188/4885HDAC4 1635/4885 |
| US-11891376-B2 | Aryl cyclopropyl-amino-isoquinolinyl amide compounds | UACA, CHUK, MAP3K2 | RAB9A 992/4885HDAC3 1221/4885HDAC4 1251/4885 |
| US-20040157865-A1 | Naphthol, quinoline and isoquinoline-derived urea modulators of vanilloid VR1 receptor | OPRL1, VRK1, OPRK1 | RAB9A 3596/4885HDAC3 3691/4885HDAC4 3041/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.