Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.76 |
| ▸ | MAPT | P10636 | 5/20 | 0.76 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | EGFR | P00533 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5659690 | 0.91 | ALDH1A1 (0.61) | ALDH1A1MAPTLMNAHTTEPHX2 | |
| SCHEMBL3211268 | 0.81 | ALDH1A1 (0.69) | ALDH1A1MAPTLMNAHTTRAB9A | |
| Hydrochloric Acid SCHEMBL3210452 | 0.80 | ALDH1A1 (0.70) | ALDH1A1MAPTLMNAHTTRAB9A | |
| SCHEMBL5337343 | 0.77 | ALDH1A1 (0.80) | ALDH1A1MAPTLMNAHTTEPHX2 | |
| SCHEMBL13234921 | 0.74 | MAPT (0.71) | ALDH1A1MAPTLMNAHTTEPHX2 | |
| SCHEMBL10122851 | 0.71 | LMNA (1.00) | ALDH1A1MAPTLMNAHTTHPGD | |
| SCHEMBL29853496 | 0.71 | ALDH1A1 (0.68) | ALDH1A1MAPTLMNAHTTEPHX2 | |
| SCHEMBL26768576 | 0.71 | ALDH1A1 (0.68) | ALDH1A1MAPTLMNAHTTEPHX2 | |
| SCHEMBL4576852 | 0.70 | SMN1; SMN2 (0.72) | ALDH1A1LMNASMN1; SMN2KDM4E | |
| SCHEMBL4261838 | 0.70 | EPHX2 (1.00) | ALDH1A1MAPTHTTEPHX2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070155727-A1 | Amide inhibitors of leukotriene A4 hydrolase | SCHERING AKTIENGESSELLSCHAFT (DE) | 2007-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070155727-A1 | Amide inhibitors of leukotriene A4 hydrolase | LTA4H, LTB4R, LTC4S | ALDH1A1 1337/4885MAPT 4374/4885LMNA 1402/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.