Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUSP3 | P51452 | 1/20 | 0.47 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | BID | P55957 | 4/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 3/20 | 0.40 |
| ▸ | BAK1 | Q16611 | 3/20 | 0.40 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18751691 | 0.83 | HSD11B1 (0.47) | HSD11B1GABRA1GABRB2KMT2AAKR1B1 | |
| SCHEMBL28769094 | 0.79 | DUSP3 (0.50) | DUSP3PTPN5PTPN11CTDSP1BID | |
| SCHEMBL423306 | 0.76 | GABRA1 (0.54) | DUSP3PTPN5PTPN11CTDSP1BID | |
| SCHEMBL13543165 | 0.76 | CTBP2 (0.51) | HSD11B1KMT2A | |
| SCHEMBL10419287 | 0.76 | AKR1B1 (0.61) | HSD11B1CA12CA2GABRA1GABRB2 | |
| SCHEMBL7943361 | 0.76 | RIPK1 (0.50) | GABRA1GABRB2 | |
| SCHEMBL8226847 | 0.76 | TDP1 (0.62) | KMT2ATDP1L3MBTL1 | |
| SCHEMBL8677292 | 0.74 | RIPK1 (0.49) | HSD11B1 | |
| SCHEMBL8446184 | 0.74 | ALDH1A1 (0.50) | SAE1KMT2A | |
| SCHEMBL19224348 | 0.74 | ALDH1A1 (0.42) | HSD11B1CA2TDP1AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060241206-A1 | Dental adhesive and dental filler | UM DENTAL CO., LTD. (JP) | 2006-10-26 | — | — | US | disclosed |
| EP-1611875-A1 | DENTAL ADHESIVE AND DENTAL FILLER | Um Dental Co., Ltd. (JP) | 2006-01-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060241206-A1 | Dental adhesive and dental filler | ICAM1, CDH1, CAD | DUSP3 4816/4885PTPN5 4851/4885PTPN11 4801/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.