SCHEMBL5675770

SCHEMBL5675770

c1cnc2c(c1)ccc1ccc3cccnc3c12

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.75
KDM4E B2RXH2 4/20 0.75
CCR1 P32246 3/20 0.75
CCR5 P51681 3/20 0.75
CCR8 P51685 3/20 0.75
MAPT P10636 3/20 0.75
MMP2 P08253 2/20 0.75
TSHR P16473 2/20 0.75
HTT P42858 2/20 0.75
SMN1; SMN2 Q16637 2/20 0.75
TDP1 Q9NUW8 2/20 0.75
GMNN O75496 1/20 0.75
TP53 P04637 1/20 0.75
HSP90AA1 P07900 1/20 0.75
CYP3A4 P08684 1/20 0.75
CYP2D6 P10635 1/20 0.75
MMP9 P14780 1/20 0.75
ALOX15 P16050 1/20 0.75
NFKB1 P19838 1/20 0.75
MMP8 P22894 1/20 0.75

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31807285 1.00 LMNA (0.75) LMNAKDM4ECCR1CCR5CCR8
Phenanthroline SCHEMBL8150927 0.89 CCR1 (0.94) LMNAKDM4ECCR1CCR5CCR8
Phenanthroline SCHEMBL29354015 0.86 CCR1 (1.00) LMNAKDM4ECCR1CCR5CCR8
Phenanthroline SCHEMBL29367277 0.86 CCR1 (1.00) LMNAKDM4ECCR1CCR5CCR8
Phenanthroline SCHEMBL8312 0.86 CCR1 (1.00) LMNAKDM4ECCR1CCR5CCR8
Phenanthroline SCHEMBL8845760 0.86 CCR1 (1.00) LMNAKDM4ECCR1CCR5CCR8
SCHEMBL3078533 0.84 LMNA (0.60) LMNAKDM4ECCR1CCR5CCR8
Phenanthroline SCHEMBL22982126 0.83 CCR1 (0.94) LMNAKDM4ECCR1CCR5CCR8
Phenanthroline SCHEMBL21060516 0.83 CCR1 (0.94) LMNAKDM4ECCR1CCR5CCR8
Phenanthroline SCHEMBL21044608 0.83 CCR1 (0.94) LMNAKDM4ECCR1CCR5CCR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240208948-A1 ORGANIC MOLECULES FOR OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2024-06-27 US disclosed
US-20240208948-A1 ORGANIC MOLECULES FOR OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2024-06-27 US disclosed
US-20240215439-A1 ORGANIC MOLECULES FOR OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2024-06-27 US disclosed
US-20240215439-A1 ORGANIC MOLECULES FOR OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2024-06-27 US disclosed
US-20240074304-A1 ORGANIC ELECTROLUMINESCENT DEVICE EMITTING BLUE LIGHT SAMSUNG DISPLAY CO., LTD. (KR) 2024-02-29 US disclosed
US-20240074309-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2024-02-29 US disclosed
US-20240032420-A1 ORGANIC ELECTROLUMINESCENT DEVICE EMITTING GREEN LIGHT SAMSUNG DISPLAY CO., LTD. (KR) 2024-01-25 US disclosed
US-20240032317-A1 ORGANIC ELECTROLUMINESCENT DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2024-01-25 US disclosed
US-20240032420-A1 ORGANIC ELECTROLUMINESCENT DEVICE EMITTING GREEN LIGHT SAMSUNG DISPLAY CO., LTD. (KR) 2024-01-25 US disclosed
US-20230380199-A1 ORGANIC ELECTROLUMINESCENT DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-11-23 US disclosed
US-20130009118-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2013-01-10 US disclosed
WO-2007022307-A2 LIGANDS FOR METAL IONS AND METHODS FOR MAKING AND USING THE SAME UNIVERSITY OF NORTH CAROLINA AT WILMINGTON (US) 2007-02-22 WO disclosed
US-20060041159-A1 Transition metal complexes with proton sponges as ligands STUDIENGESELLSCHAFT KOHLE MBH (DE) 2006-02-23 US disclosed
US-20060041159-A1 Transition metal complexes with proton sponges as ligands STUDIENGESELLSCHAFT KOHLE MBH (DE) 2006-02-23 US disclosed
EP-1353931-B1 TRANSITION METAL COMPLEXES WITH PROTON SPONGES AS LIGANDS STUDIENGESELLSCHAFT KOHLE MBH (DE) 2005-11-09 EP disclosed
EP-1353931-B1 TRANSITION METAL COMPLEXES WITH PROTON SPONGES AS LIGANDS STUDIENGESELLSCHAFT KOHLE MBH (DE) 2005-11-09 EP disclosed
EP-1353931-A1 TRANSITION METAL COMPLEXES WITH PROTON SPONGES AS LIGANDS Studiengesellschaft Kohle mbH (DE) 2003-10-22 EP disclosed
EP-1353931-A1 TRANSITION METAL COMPLEXES WITH PROTON SPONGES AS LIGANDS Studiengesellschaft Kohle mbH (DE) 2003-10-22 EP disclosed
WO-2002059134-A1 TRANSITION METAL COMPLEXES WITH PROTON SPONGES AS LIGANDS STUDIENGESELLSCHAFT KOHLE MBH (DE) 2002-08-01 WO disclosed
WO-2002059134-A1 TRANSITION METAL COMPLEXES WITH PROTON SPONGES AS LIGANDS STUDIENGESELLSCHAFT KOHLE MBH (DE) 2002-08-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240215439-A1 ORGANIC MOLECULES FOR OPTOELECTRONIC DEVICES OCIAD2, OR10J3, EPCAM LMNA 1482/4885KDM4E 3221/4885CCR1 1576/4885
US-20240208948-A1 ORGANIC MOLECULES FOR OPTOELECTRONIC DEVICES L1CAM, OCIAD2, EPCAM LMNA 834/4885KDM4E 3272/4885CCR1 1646/4885
US-20130009118-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES SOD1, L1CAM, EPCAM LMNA 2269/4885KDM4E 3217/4885CCR1 2911/4885
US-20240074309-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE PIEZO1, TMEM109, USE1 LMNA 2042/4885KDM4E 1100/4885CCR1 306/4885
US-20060041159-A1 Transition metal complexes with proton sponges as ligands HRH1, DCK, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 LMNA 3578/4885KDM4E 1923/4885CCR1 935/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.