Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | IGF1R | P08069 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.40 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6490146 | 0.86 | CASR (0.53) | CASRALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL5681763 | 0.83 | POLB (0.68) | CASRPOLBALDH1A1GAAMEN1 | |
| SCHEMBL5685489 | 0.80 | ALDH1A1 (0.71) | ALDH1A1GAAL3MBTL1KDM4EMEN1 | |
| SCHEMBL3975247 | 0.75 | TDP1 (0.46) | ALDH1A1GAAL3MBTL1KDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL7770226 | 0.74 | POLB (0.43) | POLBKDM4EKMT2ATDP1ADRB2 | |
| SCHEMBL4625449 | 0.73 | ALOX5 (0.40) | POLBALDH1A1GAAL3MBTL1MEN1 | |
| SCHEMBL335111 | 0.72 | KMT2A (0.47) | POLBALDH1A1GAAL3MBTL1KDM4E | |
| SCHEMBL22342333 | 0.72 | CASR (0.71) | CASRPOLBALDH1A1L3MBTL1MEN1 | |
| SCHEMBL12603587 | 0.72 | CASR (0.71) | CASRPOLBALDH1A1L3MBTL1MEN1 | |
| SCHEMBL7181502 | 0.72 | CASR (0.62) | CASRPOLBALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1359891-B1 | PRIMARY INTERMEDIATES FOR OXIDATIVE COLORATION OF HAIR | P & G CLAIROL INC (US) | 2006-03-15 | — | — | EP | disclosed |
| US-6838561-B2 | Primary intermediates for oxidative coloration of hair | THE PROCTER & GAMBLE COMPANY (US) | 2005-01-04 | — | — | US | disclosed |
| EP-1359891-A4 | PRIMARY INTERMEDIATES FOR OXIDATIVE COLORATION OF HAIR | P & G CLAIROL INC (US) | 2004-12-01 | — | — | EP | disclosed |
| EP-1359891-A2 | PRIMARY INTERMEDIATES FOR OXIDATIVE COLORATION OF HAIR | P&G-Clairol, Inc. (US) | 2003-11-12 | — | — | EP | disclosed |
| US-20020144358-A1 | Primary intermediates for oxidative coloration of hair | WELLA OPERATIONS US, LLC | 2002-10-10 | — | — | US | disclosed |
| WO-2002062308-A2 | PRIMARY INTERMEDIATES FOR OXIDATIVE COLORATION OF HAIR | P&G-CLAIROL, INC. (US) | 2002-08-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020144358-A1 | Primary intermediates for oxidative coloration of hair | COX5A, CYC1, MT-CO1 | CASR 4857/4885POLB 261/4885ALDH1A1 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.