SCHEMBL5685689

SCHEMBL5685689

Clc1ccccc1Sc1cc[c]cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.41
HAO1 Q9UJM8 1/20 0.41
RHEB Q15382 1/20 0.40
PDE7A Q13946 2/20 0.38
PRMT1 Q99873 1/20 0.37
LMNA P02545 3/20 0.36
TSHR P16473 1/20 0.36
KDM4E B2RXH2 2/20 0.36
NPSR1 Q6W5P4 2/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
PKM P14618 1/20 0.36
DHFR P00374 1/20 0.36
ALDH1A1 P00352 1/20 0.36
MAPT P10636 1/20 0.36
KMT2A Q03164 2/20 0.35
MEN1 O00255 1/20 0.35
SLC6A4 P31645 1/20 0.35
TDP1 Q9NUW8 2/20 0.35
RXFP1 Q9HBX9 1/20 0.35
PRMT3 O60678 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3784489 0.82 PDE7A (0.50) HPGDHAO1RHEBPDE7APRMT1
SCHEMBL8433301 0.78 MEN1 (0.57) HPGDHAO1RHEBPDE7ALMNA
SCHEMBL6915666 0.77 RHEB (0.55) HPGDHAO1RHEBPRMT1LMNA
SCHEMBL29543966 0.77 RHEB (0.55) HPGDHAO1RHEBPRMT1LMNA
SCHEMBL1691711 0.76 PDE7A (0.39) HPGDPDE7ALMNAKDM4EL3MBTL1
SCHEMBL5687892 0.75 PGR (0.44) HAO1LMNAKDM4EL3MBTL1ALDH1A1
SCHEMBL5685312 0.75 LMNA (0.41) PDE7ALMNAKDM4EALDH1A1MAPT
SCHEMBL4612772 0.75 CYP3A4 (0.48) HPGDPDE7ALMNAKDM4ENPSR1
SCHEMBL3893766 0.75 SIRT1 (0.36) HPGDLMNATSHRKDM4EL3MBTL1
SCHEMBL5685707 0.75 AR (0.43) HAO1TSHRL3MBTL1ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060122064-A1 Amides and method for plant diseases control with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-06-08 US disclosed
EP-1640360-A1 AMIDES AND METHOD FOR PLANT DISEASE CONTROL WITH THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-03-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060122064-A1 Amides and method for plant diseases control with the same ARG1, ARGLU1, ARG2 HPGD 3826/4885HAO1 1047/4885RHEB 270/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.