Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | PDE9A | O76083 | 1/20 | 0.51 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | CRHBP | P24387 | 1/20 | 0.48 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CCR2 | P41597 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | CASP6 | P55212 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18582737 | 0.89 | PDE9A (0.62) | ALDH1A1KDM4EHSD17B10PDE9APDE1C | |
| SCHEMBL22864939 | 0.87 | PDE9A (0.67) | ALDH1A1KDM4EHSD17B10PDE9APDE1C | |
| SCHEMBL18608868 | 0.87 | PDE9A (0.51) | ALDH1A1KDM4EPDE9APDE1CMEN1 | |
| SCHEMBL568696 | 0.86 | ALDH1A1 (0.52) | ALDH1A1KDM4EHSD17B10PDE9APDE1C | |
| SCHEMBL14375754 | 0.82 | PDE9A (0.49) | ALDH1A1KDM4EHSD17B10PDE9APDE1C | |
| SCHEMBL11372084 | 0.80 | L3MBTL1 (0.63) | ALDH1A1KDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL23411350 | 0.78 | KDM4E (0.64) | ALDH1A1KDM4EHSD17B10MEN1KMT2A | |
| SCHEMBL29891520 | 0.78 | KDM4E (0.64) | ALDH1A1KDM4EHSD17B10MEN1KMT2A | |
| SCHEMBL11445217 | 0.78 | KMT2A (0.81) | ALDH1A1KDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL5529427 | 0.77 | HTR3A (0.50) | ALDH1A1KDM4EHSD17B10PDE9APDE1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11964987-B2 | Isoidide derivatives and methods of making and using same | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2024-04-23 | — | — | US | disclosed |
| US-20210002291-A1 | ISOIDIDE DERIVATIVES AND METHODS OF MAKING AND USING SAME | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2021-01-07 | — | — | US | disclosed |
| US-20210002291-A1 | ISOIDIDE DERIVATIVES AND METHODS OF MAKING AND USING SAME | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2021-01-07 | — | — | US | disclosed |
| US-10815244-B2 | Isoidide derivatives and methods of making and using same | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2020-10-27 | — | — | US | disclosed |
| US-10815244-B2 | Isoidide derivatives and methods of making and using same | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2020-10-27 | — | — | US | disclosed |
| EP-3354640-A2 | MIF INHIBITORS AND THEIR USES | Innovimmune Biotherapeutics, Inc. (US) | 2018-08-01 | — | — | EP | disclosed |
| EP-3354640-A2 | MIF INHIBITORS AND THEIR USES | Innovimmune Biotherapeutics, Inc. (US) | 2018-08-01 | — | — | EP | disclosed |
| EP-2696682-B1 | MIF INHIBITORS AND THEIR USES | INNOVIMMUNE BIOTHERAPEUTICS INC (US) | 2018-03-21 | — | — | EP | disclosed |
| EP-2696682-B1 | MIF INHIBITORS AND THEIR USES | INNOVIMMUNE BIOTHERAPEUTICS INC (US) | 2018-03-21 | — | — | EP | disclosed |
| EP-2592933-B1 | MIF INHIBITORS AND THEIR USES | GAWECO ANDERSON (US) | 2017-04-05 | — | — | EP | disclosed |
| US-20120035150-A1 | MIF INHIBITORS AND THEIR USES | INNOV88 LLC | 2012-02-09 | — | — | US | disclosed |
| US-20120035150-A1 | MIF INHIBITORS AND THEIR USES | INNOV88 LLC | 2012-02-09 | — | — | US | disclosed |
| US-20120035150-A1 | MIF INHIBITORS AND THEIR USES | INNOV88 LLC | 2012-02-09 | — | — | US | disclosed |
| WO-2012009649-A1 | MIF INHIBITORS AND THEIR USES | GAWECO ANDERSON (US) | 2012-01-19 | — | — | WO | disclosed |
| US-7235546-B2 | Inhibitors of macrophage migration inhibitory factor and methods for identifying the same | AVANIR PHARMACEUTICALS (US) | 2007-06-26 | — | — | US | disclosed |
| US-7235546-B2 | Inhibitors of macrophage migration inhibitory factor and methods for identifying the same | AVANIR PHARMACEUTICALS (US) | 2007-06-26 | — | — | US | disclosed |
| US-20070054898-A1 | Inhibitors of macrophage migration inhibitory factor and methods for identifying the same | AVANIR PHARMACEUTICALS | 2007-03-08 | — | — | US | disclosed |
| US-20070054898-A1 | Inhibitors of macrophage migration inhibitory factor and methods for identifying the same | AVANIR PHARMACEUTICALS | 2007-03-08 | — | — | US | disclosed |
| US-7173036-B2 | Inhibitors of macrophage migration inhibitory factor and methods for identifying the same | AVANIR PHARMACEUTICALS (US) | 2007-02-06 | — | — | US | disclosed |
| US-7173036-B2 | Inhibitors of macrophage migration inhibitory factor and methods for identifying the same | AVANIR PHARMACEUTICALS (US) | 2007-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120035150-A1 | MIF INHIBITORS AND THEIR USES | MIF, SERPINB1, HMGB2 | ALDH1A1 790/4885KDM4E 4189/4885HSD17B10 2121/4885 |
| US-11964987-B2 | Isoidide derivatives and methods of making and using same | MIF, ITGB7, ITGB4 | ALDH1A1 1018/4885KDM4E 1574/4885HSD17B10 3272/4885 |
| US-20070054898-A1 | Inhibitors of macrophage migration inhibitory factor and methods for identifying the same | MIF, MSR1, MMP12 | ALDH1A1 1799/4885KDM4E 2968/4885HSD17B10 3007/4885 |
| US-10815244-B2 | Isoidide derivatives and methods of making and using same | MIF, ITGB7, ITGB4 | ALDH1A1 1018/4885KDM4E 1574/4885HSD17B10 3272/4885 |
| US-20210002291-A1 | ISOIDIDE DERIVATIVES AND METHODS OF MAKING AND USING SAME | MIF, ITGB7, ITGB4 | ALDH1A1 1018/4885KDM4E 1574/4885HSD17B10 3272/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.