SCHEMBL5687906

SCHEMBL5687906

COc1cc(CCC(=O)O)ccc1OCCF

nearest known ligand 0.57

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 2/20 0.57
FFAR4 Q5NUL3 4/20 0.57
FFAR1 O14842 2/20 0.55
PDE10A Q9Y233 5/20 0.55
PDE3B Q13370 3/20 0.55
PDE3A Q14432 3/20 0.55
APP P05067 2/20 0.53
LMNA P02545 1/20 0.51
FFAR2 O15552 1/20 0.50
PLA2G4A P47712 1/20 0.48
HDAC1 Q13547 1/20 0.48
HDAC2 Q92769 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22622262 0.91 LMNA (0.62) PPARAFFAR4FFAR1APPLMNA
SCHEMBL3693650 0.89 LMNA (0.60) PPARAFFAR4FFAR1APPLMNA
SCHEMBL347209 0.86 FFAR4 (0.61) FFAR4FFAR1PLA2G4A
SCHEMBL3690496 0.85 CALM1 (0.60) PPARAFFAR4FFAR1APPPLA2G4A
SCHEMBL8133000 0.85 KDM4E (0.57) PPARAFFAR4FFAR1APPLMNA
Hydrochloric Acid SCHEMBL3225386 0.85 FFAR4 (0.59) FFAR4FFAR1PLA2G4A
SCHEMBL9178046 0.84 FFAR4 (0.55) PPARAFFAR4FFAR1APPFFAR2
SCHEMBL5685578 0.84 CYP4F2 (0.54) PDE10APDE3BPDE3AAPPLMNA
SCHEMBL31322145 0.83 ALOX5 (0.62) PPARAFFAR4FFAR1APPLMNA
SCHEMBL3974023 0.82 FFAR4 (0.51) PPARAFFAR4FFAR1APPLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060122064-A1 Amides and method for plant diseases control with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-06-08 US disclosed
EP-1640360-A1 AMIDES AND METHOD FOR PLANT DISEASE CONTROL WITH THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-03-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060122064-A1 Amides and method for plant diseases control with the same ARG1, ARGLU1, ARG2 PPARA 1528/4885FFAR4 3414/4885FFAR1 1641/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.