Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CASP1 | P29466 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8464915 | 0.82 | ALDH1A1 (0.47) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL5707641 | 0.78 | ALDH1A1 (0.46) | ALDH1A1CASP1KDM4ETP53MAPT | |
| SCHEMBL30462573 | 0.78 | ALDH1A1 (0.52) | ALDH1A1CASP1KDM4ETP53MAPT | |
| SCHEMBL4532343 | 0.78 | ALDH1A1 (0.52) | ALDH1A1CASP1KDM4ETP53MAPT | |
| SCHEMBL599354 | 0.76 | GAA (0.50) | ALDH1A1CASP1KDM4ETP53MAPT | |
| SCHEMBL27746114 | 0.75 | ALDH1A1 (0.44) | ALDH1A1CASP1KDM4ETP53MAPT | |
| SCHEMBL23581678 | 0.74 | ALDH1A1 (0.50) | ALDH1A1CASP1KDM4ETP53MAPT | |
| SCHEMBL5317178 | 0.74 | ALDH1A1 (0.50) | ALDH1A1CASP1KDM4ETP53MAPT | |
| SCHEMBL8515345 | 0.74 | MEN1 (0.58) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL27734367 | 0.74 | CASP1 (0.47) | ALDH1A1CASP1KDM4ETP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1357889-B1 | NOVELS COUPLERS FOR USE IN OXIDATIVE HAIR DYEING | P & G CLAIROL INC (US) | 2006-04-05 | — | — | EP | disclosed |
| EP-1357889-A4 | NOVELS COUPLERS FOR USE IN OXIDATIVE HAIR DYEING | P & G CLAIROL INC (US) | 2004-12-01 | — | — | EP | disclosed |
| US-6693196-B2 | BIS(2,4-DIAMINOPHENOXY)PYRIDINES AND PYRIMIDINES | THE PROCTER & GAMBLE COMPANY | 2004-02-17 | — | — | US | disclosed |
| EP-1357889-A1 | NOVELS COUPLERS FOR USE IN OXIDATIVE HAIR DYEING | P&G-Clairol, Inc. (US) | 2003-11-05 | — | — | EP | disclosed |
| US-20030061667-A1 | Novel couplers for use in oxidative hair dyeing | WELLA OPERATIONS US, LLC | 2003-04-03 | — | — | US | disclosed |
| WO-2002060400-A1 | NOVELS COUPLERS FOR USE IN OXIDATIVE HAIR DYEING | P&G-CLAIROL, INC. (US) | 2002-08-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030061667-A1 | Novel couplers for use in oxidative hair dyeing | PYCR1, MT-CO3, MT-CO1 | ALDH1A1 133/4885CASP1 848/4885KDM4E 1617/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.