Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD5 | P21918 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7477308 | 0.81 | GRM2 (0.43) | SMN1; SMN2HDAC1HDAC6CCR5ECE1 | |
| SCHEMBL5708660 | 0.80 | DRD2 (0.40) | ALDH1A1MAPTDRD2DRD3HDAC1 | |
| SCHEMBL5708655 | 0.79 | MAOA (0.47) | KDM4EMEN1ALDH1A1TP53ADRB1 | |
| SCHEMBL5708664 | 0.75 | MAOA (0.48) | TP53MAPTMAOAMAOB | |
| SCHEMBL8653482 | 0.74 | HDAC1 (0.30) | HDAC1HDAC6 | |
| SCHEMBL9263854 | 0.73 | ALDH1A1 (0.55) | KDM4EMEN1ALDH1A1TP53ADRB1 | |
| SCHEMBL9263846 | 0.73 | ALDH1A1 (0.55) | KDM4EMEN1ALDH1A1TP53ADRB1 | |
| SCHEMBL5908275 | 0.72 | METTL3 (0.33) | ALDH1A1HDAC1HDAC6CCR5 | |
| SCHEMBL20171376 | 0.68 | RAB9A (0.51) | MEN1ALDH1A1TP53MAPTHPGD | |
| SCHEMBL5020713 | 0.67 | MAOA (0.56) | ALDH1A1CYP3A4MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0999209-B1 | 2-SULFAMOYLBENZOIC ACID DERIVATIVES | KAKEN PHARMA CO LTD (JP) | 2006-11-02 | — | — | EP | disclosed |
| US-20020049228-A1 | 2-Sulfamoylbenzoic acid derivatives | KAKEN PHARMACEUTICALS | 2002-04-25 | — | — | US | disclosed |
| US-6376671-B1 | LEUKOTRIENE AND THROMBOXANE A2 ANTAGONISTIC AGENTS; ANTIALLERGIC AGENTS | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 2002-04-23 | — | — | US | disclosed |
| US-6255321-B1 | ANTIALLERGENS; RESPIRATRORY SYSTEM DISORDERS | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 2001-07-03 | — | — | US | disclosed |
| EP-0999209-A1 | 2-SULFAMOYLBENZOIC ACID DERIVATIVES | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 2000-05-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020049228-A1 | 2-Sulfamoylbenzoic acid derivatives | LTB4R2, LTB4R, CYSLTR2 | KDM4E 3733/4885MEN1 3704/4885ALDH1A1 810/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.