SCHEMBL571123

SCHEMBL571123

CC(C)(C)OP(=O)(O)OP(=O)(O)OC(C)(C)C

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.36
FDPS P14324 2/20 0.35
BLM P54132 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
P2RY14 Q15391 2/20 0.32
CA2 P00918 1/20 0.32
P2RY6 Q15077 1/20 0.32
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12234256 0.90 FDPS (0.41) LMNAFDPSBLMTDP1
SCHEMBL2871051 0.89 FDPS (0.45) LMNAFDPSBLMTDP1
Hydrochloric Acid SCHEMBL28697610 0.88 FDPS (0.39) FDPSBLMTDP1
SCHEMBL243552 0.88 LMNA (0.40) LMNAFDPSBLMTDP1CA2
SCHEMBL18470972 0.87 CA2 (0.33) LMNAFDPSBLMTDP1CA2
SCHEMBL553541 0.85 LMNA (0.38) LMNAFDPSBLMTDP1CA2
SCHEMBL555010 0.85 LMNA (0.38) LMNAFDPSBLMTDP1CA2
SCHEMBL695544 0.85 LMNA (0.38) LMNAFDPSBLMTDP1CA2
SCHEMBL3080683 0.83
SCHEMBL19050963 0.82 CTSA (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240218011-A1 GLUCOCORTICOID RECEPTOR AGONISTS AND CONJUGATES THEREOF FIREFLY BIO, INC. 2024-07-04 US disclosed
US-20240067640-A1 PHENYL MALEIMIDE LINKER AGENTS FIREFLY BIO, INC. 2024-02-29 US disclosed
US-9826129-B2 Near-infrared-ray-absorbing composition, near-infrared-ray cut filter using same, manufacturing method therefor, camera module, and manufacturing method therefor FUJIFILM CORPORATION (JP) 2017-11-21 US disclosed
US-9826129-B2 Near-infrared-ray-absorbing composition, near-infrared-ray cut filter using same, manufacturing method therefor, camera module, and manufacturing method therefor FUJIFILM CORPORATION (JP) 2017-11-21 US disclosed
US-20170182181-A1 PHOSPHATE BASED LINKERS FOR INTRACELLULAR DELIVERY OF DRUG CONJUGATES MERCK SHARP & DOHME CORP. (US) 2017-06-29 US disclosed
US-20160037034-A1 NEAR-INFRARED-RAY-ABSORBING COMPOSITION, NEAR-INFRARED-RAY CUT FILTER USING SAME, MANUFACTURING METHOD THEREFOR, CAMERA MODULE, AND MANUFACTURING METHOD THEREFOR FUJIFILM CORPORATION (JP) 2016-02-04 US disclosed
US-20160037034-A1 NEAR-INFRARED-RAY-ABSORBING COMPOSITION, NEAR-INFRARED-RAY CUT FILTER USING SAME, MANUFACTURING METHOD THEREFOR, CAMERA MODULE, AND MANUFACTURING METHOD THEREFOR FUJIFILM CORPORATION (JP) 2016-02-04 US disclosed
EP-2601177-A1 N-ACYLSULFONAMIDE APOPTOSIS PROMOTERS AstraZeneca AB (SE) 2013-06-12 EP disclosed
WO-2012017251-A1 N-ACYLSULFONAMIDE APOPTOSIS PROMOTERS ASTRAZENECA AB (SE) 2012-02-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170182181-A1 PHOSPHATE BASED LINKERS FOR INTRACELLULAR DELIVERY OF DRUG CONJUGATES CD47, PLPBP, CHERP LMNA 1946/4885FDPS 1631/4885BLM 4171/4885
US-20160037034-A1 NEAR-INFRARED-RAY-ABSORBING COMPOSITION, NEAR-INFRARED-RAY CUT FILTER USING SAME, MANUFACTURING METHOD THEREFOR, CAMERA MODULE, AND MANUFACTURING METHOD THEREFOR FAR1, SLC39A11, NOTUM LMNA 2313/4885FDPS 827/4885BLM 1196/4885
US-20240218011-A1 GLUCOCORTICOID RECEPTOR AGONISTS AND CONJUGATES THEREOF NR3C1, NR3C2, MC2R LMNA 4639/4885FDPS 3338/4885BLM 1775/4885
US-20240067640-A1 PHENYL MALEIMIDE LINKER AGENTS TPX2, H1-4, MAPT LMNA 233/4885FDPS 4061/4885BLM 1932/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.