Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.46 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NNMT | P40261 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.40 |
| ▸ | BRS3 | P32247 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | G6PD | P11413 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30613366 | 0.81 | NNMT (0.50) | GPR52TAS2R14MEN1KMT2ANNMT | |
| SCHEMBL29024632 | 0.80 | USP2 (0.54) | NPC1USP2BRS3TSHRG6PD | |
| SCHEMBL3361331 | 0.75 | TSHR (0.57) | TSHRG6PDCASP7CASP6 | |
| SCHEMBL4444648 | 0.74 | G6PD (0.59) | LMNATSHRG6PDCASP7CASP6 | |
| SCHEMBL30934865 | 0.74 | G6PD (0.59) | LMNATSHRG6PDCASP7CASP6 | |
| SCHEMBL16598239 | 0.73 | NNMT (0.48) | GPR52TAS2R14MEN1KMT2ANNMT | |
| SCHEMBL28748299 | 0.73 | MEN1 (0.45) | GPR52TAS2R14MEN1KMT2ANNMT | |
| SCHEMBL7781040 | 0.73 | TSHR (0.51) | LMNATSHRG6PDCASP7CASP6 | |
| SCHEMBL8517324 | 0.72 | ALDH1A1 (0.68) | MEN1KMT2ALMNAPKMUSP2 | |
| SCHEMBL7283731 | 0.71 | LTA4H (0.47) | MEN1KMT2ANPC1LMNAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1697312-A2 | HYDROXAMIC ACID ESTERS AND PHARMACEUTICAL USE THEREOF | Leo Pharma A/S (DK) | 2006-09-06 | — | — | EP | disclosed |
| WO-2005054179-A2 | HYDROXAMIC ACID ESTERS AND PHARMACEUTICAL USE THEREOF | LEO PHARMA A/S (DK) | 2005-06-16 | — | — | WO | disclosed |