SCHEMBL572237

SCHEMBL572237

O=C1Oc2cc(O)c(O)cc2CC1c1ccc(O)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX12 P18054 4/20 0.52
ALOX15 P16050 3/20 0.52
ALOX15B O15296 2/20 0.52
ESR1 P03372 2/20 0.42
ESR2 Q92731 2/20 0.42
KMT2A Q03164 5/20 0.41
ALDH1A1 P00352 5/20 0.41
MEN1 O00255 4/20 0.41
CYP19A1 P11511 3/20 0.41
HPGD P15428 2/20 0.41
MAPT P10636 2/20 0.41
GLA P06280 1/20 0.41
THRB P10828 1/20 0.41
CYP3A4 P08684 3/20 0.40
HSD17B10 Q99714 3/20 0.40
CA12 O43570 1/20 0.40
SLCO2B1 O94956 1/20 0.40
TTR P02766 1/20 0.40
SHBG P04278 1/20 0.40
CYP1A1 P04798 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2030055 0.86 ESR2 (0.51) ALOX12ALOX15ESR1ESR2KMT2A
SCHEMBL3357789 0.85 ALOX15 (0.57) ALOX12ALOX15KMT2AALDH1A1MEN1
SCHEMBL17938760 0.82 MAPT (0.56) ALOX15ESR1ESR2KMT2AALDH1A1
SCHEMBL4806205 0.80 MAPT (0.46) ALOX12ESR1ESR2KMT2AALDH1A1
SCHEMBL10685633 0.78 ALDH1A1 (0.55) ALOX15ESR1ESR2KMT2AALDH1A1
SCHEMBL3493652 0.78 ESR1 (0.55) ALOX12ALOX15ESR1ESR2KMT2A
SCHEMBL10681542 0.78 ALDH1A1 (0.58) ESR1ESR2KMT2AALDH1A1MEN1
SCHEMBL5847123 0.77 ESR2 (0.43) ALOX12ALOX15ESR1ESR2KMT2A
SCHEMBL2069508 0.75 ALDH1A1 (0.59) ALOX12ALOX15KMT2AALDH1A1MEN1
SCHEMBL17938826 0.75 ALOX12 (0.42) ALOX12ALOX15ESR1ESR2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12163004-B2 Polymer composites WARNER BABCOCK INSTITUTE FOR GREEN CHEMISTRY, LLC (US) 2024-12-10 US claimed
US-20250051551-A1 IMPROVED POLYMER COMPOSITES WARNER BABCOCK INSTITUTE FOR GREEN CHEMISTRY, LLC (US) 2025-02-13 US disclosed
US-12163004-B2 Polymer composites WARNER BABCOCK INSTITUTE FOR GREEN CHEMISTRY, LLC (US) 2024-12-10 US disclosed
US-20240355451-A1 METHODS FOR IMPROVING GUT MICROBIOTA DIVERSITY NESTLE SA (CH) 2024-10-24 US disclosed
US-20240101791-A1 POLYMER COMPOSITES WARNER BABCOCK INSTITUTE FOR GREEN CHEMISTRY, LLC (US) 2024-03-28 US disclosed
WO-2024059282-A1 IMPROVED POLYMER COMPOSITES WARNER BABCOCK INSTITUTE FOR GREEN CHEMISTRY, LLC (US) 2024-03-21 WO disclosed
EP-3862002-A1 GLYCAN THERAPEUTICS AND RELATED METHODS THEREOF Kaleido Biosciences, Inc. (US) 2021-08-11 EP disclosed
EP-3354282-B1 GLYCAN THERAPEUTICS AND RELATED METHODS THEREOF KALEIDO BIOSCIENCES INC (US) 2020-12-30 EP disclosed
EP-3354282-A1 GLYCAN THERAPEUTICS AND RELATED METHODS THEREOF Kaleido Biosciences, Inc. (US) 2018-08-01 EP disclosed
EP-3334437-A1 GLYCAN COMPOSITIONS AND USES THEREOF Kaleido Biosciences, Inc. (US) 2018-06-20 EP disclosed
US-20110301105-A1 COMPOSITIONS FOR PROLIFERATION OF CELLS AND RELATED METHODS THE HOSPITAL FOR SICK CHILDREN (CA) 2011-12-08 US disclosed
WO-2010039679-A1 COMPOSITIONS FOR PROLIFERATION OF CELLS AND RELATED METHODS THE HOSPITAL FOR SICK CHILDREN (CA) 2010-04-08 WO disclosed
EP-1670485-A4 TREATMENT OF DISEASES ASSOCIATED WITH THE EGR-1 ENHANCER ELEMENT RESVERLOGIX CORP (CA) 2009-03-11 EP disclosed
US-20070099826-A1 Treatment of diseases associated with the egr-1 enhancer element RESVERLOGIX CORP. (CA) 2007-05-03 US disclosed
EP-1670484-A1 NITRIC OXIDE DONATING DERIVATIVES FOR THE TREATMENT OF CARDIOVASCULAR DISORDERS RESVERLOGIX CORP. (CA) 2006-06-21 EP disclosed
EP-1670485-A1 TREATMENT OF DISEASES ASSOCIATED WITH THE EGR-1 ENHANCER ELEMENT RESVERLOGIX CORP. (CA) 2006-06-21 EP disclosed
WO-2005034960-A1 TREATMENT OF DISEASES ASSOCIATED WITH THE EGR-1 ENHANCER ELEMENT RESVERLOGIX CORP. (CA) 2005-04-21 WO disclosed
US-20050080024-A1 Nitric oxide donating derivatives for the treatment of cardiovascular disorders RESVERLOGIX CORP. (CA) 2005-04-14 US disclosed
US-20050080021-A1 Nitric oxide donating derivatives of stilbenes, polyphenols and flavonoids for the treatment of cardiovascular disorders RESVERLOGIX CORP. (CA) 2005-04-14 US disclosed
WO-2005032559-A1 NITRIC OXIDE DONATING DERIVATIVES FOR THE TREATMENT OF CARDIOVASCULAR DISORDERS RESVERLOGIX CORP. (CA) 2005-04-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050080024-A1 Nitric oxide donating derivatives for the treatment of cardiovascular disorders NOS2, NOS3, NOS1 ALOX12 191/4885ALOX15 206/4885ALOX15B 198/4885
US-20070099826-A1 Treatment of diseases associated with the egr-1 enhancer element TOE1, ATF1, ELF3 ALOX12 1093/4885ALOX15 1155/4885ALOX15B 1087/4885
US-20050080021-A1 Nitric oxide donating derivatives of stilbenes, polyphenols and flavonoids for the treatment of cardiovascular disorders NOS2, NOS1, NOS3 ALOX12 218/4885ALOX15 265/4885ALOX15B 241/4885
US-20110301105-A1 COMPOSITIONS FOR PROLIFERATION OF CELLS AND RELATED METHODS MKI67, KRT18, PROX1 ALOX12 3429/4885ALOX15 3682/4885ALOX15B 3352/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.