SCHEMBL572390

SCHEMBL572390

O=[N+]([O-])c1ccc2c(c1)Cc1cc(F)ccc1-2

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TLR9 Q9NR96 2/20 0.66
MEN1 O00255 1/20 0.66
LMNA P02545 1/20 0.66
MAPT P10636 1/20 0.66
RAB9A P51151 1/20 0.66
KMT2A Q03164 1/20 0.66
TDP2 O95551 1/20 0.54
CRHBP P24387 1/20 0.53
CRHR2 Q13324 1/20 0.53
HSP90AA1 P07900 1/20 0.50
PGR P06401 2/20 0.49
PTPRC P08575 1/20 0.46
S100A4 P26447 1/20 0.46
ATM Q13315 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
ADRA2A P08913 2/20 0.45
PNMT P11086 2/20 0.45
PARP1 P09874 1/20 0.45
ALDH1A1 P00352 1/20 0.44
HIF1A Q16665 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9811059 0.93 TLR9 (0.62) TLR9MEN1LMNAMAPTRAB9A
SCHEMBL987760 0.89 TLR9 (0.79) TLR9MEN1LMNAMAPTRAB9A
SCHEMBL30049268 0.89 TLR9 (0.79) TLR9MEN1LMNAMAPTRAB9A
2-Nitrofluorene SCHEMBL29450702 0.81 MAPT (0.68) TLR9MEN1LMNAMAPTRAB9A
2-Nitrofluorene SCHEMBL644332 0.81 MAPT (0.68) TLR9MEN1LMNAMAPTRAB9A
SCHEMBL5030144 0.79 TLR9 (0.66) TLR9MEN1LMNAMAPTRAB9A
SCHEMBL2374341 0.79 MAPT (1.00) TLR9MEN1LMNAMAPTRAB9A
SCHEMBL8927848 0.79 TLR9 (0.66) TLR9MEN1LMNAMAPTRAB9A
SCHEMBL5528874 0.79 TLR9 (0.66) TLR9MEN1LMNAMAPTRAB9A
SCHEMBL18849687 0.79 TLR9 (0.66) TLR9MEN1LMNAMAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113711007-B Method for determining generation source of microparticles in atmosphere 株式会社岛津制作所 2024-10-25 CN claimed
CN-113711007-A Method for determining generation source of fine particles in atmosphere 株式会社岛津制作所 2021-11-26 CN claimed
WO-2020217543-A1 METHOD FOR IDENTIFYING GENERATION SOURCES OF FINE PARTICULATES IN ATMOSPHERE 早川 和一 2020-10-29 WO claimed
CN-113711007-B Method for determining generation source of microparticles in atmosphere 株式会社岛津制作所 2024-10-25 CN disclosed
US-20230149340-A1 BISMUTH-THIOLS AS ANTISEPTICS FOR EPITHELIAL TISSUES, ACUTE AND CHRONIC WOUNDS, BACTERIAL BIOFILMS AND OTHER INDICATIONS MICROBION CORPORATION 2023-05-18 US disclosed
US-11564903-B2 Bismuth-thiols as antiseptics for epithelial tissues, acute and chronic wounds, bacterial biofilms and other indications MICROBION CORPORATION (US) 2023-01-31 US disclosed
US-20220016132-A1 BISMUTH-THIOLS AS ANTISEPTICS FOR BIOMEDICAL USES, INCLUDING TREATMENT OF BACTERIAL BIOFILMS AND OTHER USES MICROBION CORPORATION 2022-01-20 US disclosed
CN-113711007-A Method for determining generation source of fine particles in atmosphere 株式会社岛津制作所 2021-11-26 CN disclosed
US-10960012-B2 Bismuth-thiols as antiseptics for biomedical uses, including treatment of bacterial biofilms and other uses MICROBION CORPORATION (US) 2021-03-30 US disclosed
US-10835510-B2 Bismuth-thiols as antiseptics for epithelial tissues, acute and chronic wounds, bacterial biofilms and other indications MICROBION CORPORATION (US) 2020-11-17 US disclosed
WO-2020217543-A1 METHOD FOR IDENTIFYING GENERATION SOURCES OF FINE PARTICULATES IN ATMOSPHERE 早川 和一 2020-10-29 WO disclosed
US-20080268514-A1 Liquid matrix dissolved or dissociated in biocompatible solvent and stabilizer in contact without refrigeration for one day EXACT SCIENCES CORPORATION 2008-10-30 US disclosed
EP-1951868-A2 INTEGRATION OF SAMPLE STORAGE AND SAMPLE MANAGEMENT FOR LIFE SCIENCE Biomatrica, Inc. (US) 2008-08-06 EP disclosed
US-20080176209-A1 INTEGRATION OF SAMPLE STORAGE AND SAMPLE MANAGEMENT FOR LIFE SCIENCE BIOMATRICA, INC. (US) 2008-07-24 US disclosed
CN-101035620-A Integration of sample storage and sample management for life sciences BIOMATRICA INC (US) 2007-09-12 CN disclosed
WO-2007075253-A2 INTEGRATION OF SAMPLE STORAGE AND SAMPLE MANAGEMENT FOR LIFE SCIENCE BIOMATRICA, INC. (US) 2007-07-05 WO disclosed
EP-1737573-A2 INTEGRATION OF SAMPLE STORAGE AND SAMPLE MANAGEMENT FOR LIFE SCIENCE Biomatrica, Inc. (US) 2007-01-03 EP disclosed
US-20060099567-A1 Desolventizing, dehydration, dryness; for automated storing, tracking retrieving and analyzing of nucleic acid samples; refrigeration-free BIOMATRICA, INC. (US) 2006-05-11 US disclosed
US-20050276728-A1 Desolventizing, dehydration, dryness; for automated storing, tracking retrieving and analyzing of nucleic acid samples; refrigeration-free BIOMATRICA, INC. (US) 2005-12-15 US disclosed
WO-2005113147-A2 INTEGRATION OF SAMPLE STORAGE AND SAMPLE MANAGEMENT FOR LIFE SCIENCE BIOMATRICA, INC. (US) 2005-12-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10960012-B2 Bismuth-thiols as antiseptics for biomedical uses, including treatment of bacterial biofilms and other uses TST, BTD, BTF3 TLR9 1158/4885MEN1 1986/4885LMNA 4868/4885
US-20220016132-A1 BISMUTH-THIOLS AS ANTISEPTICS FOR BIOMEDICAL USES, INCLUDING TREATMENT OF BACTERIAL BIOFILMS AND OTHER USES TST, BTD, BTF3 TLR9 1158/4885MEN1 1986/4885LMNA 4868/4885
US-20230149340-A1 BISMUTH-THIOLS AS ANTISEPTICS FOR EPITHELIAL TISSUES, ACUTE AND CHRONIC WOUNDS, BACTERIAL BIOFILMS AND OTHER INDICATIONS TST, BTD, BTF3 TLR9 467/4885MEN1 3276/4885LMNA 4876/4885
US-20060099567-A1 Desolventizing, dehydration, dryness; for automated storing, tracking retrieving and analyzing of nucleic acid samples; refrigeration-free DNASE1, DCTD, DNASE1L3 TLR9 4221/4885MEN1 3794/4885LMNA 860/4885
US-20080176209-A1 INTEGRATION OF SAMPLE STORAGE AND SAMPLE MANAGEMENT FOR LIFE SCIENCE NEFM, DNASE1, DCTD TLR9 3851/4885MEN1 2408/4885LMNA 191/4885
US-10835510-B2 Bismuth-thiols as antiseptics for epithelial tissues, acute and chronic wounds, bacterial biofilms and other indications TST, BTD, BTF3 TLR9 467/4885MEN1 3276/4885LMNA 4876/4885
US-11564903-B2 Bismuth-thiols as antiseptics for epithelial tissues, acute and chronic wounds, bacterial biofilms and other indications TST, BTD, BTF3 TLR9 467/4885MEN1 3276/4885LMNA 4876/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.