Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | SCD | O00767 | 3/20 | 0.40 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5738747 | 0.92 | MAOB (0.42) | MAOBGPR52MEN1MAPTKMT2A | |
| SCHEMBL5739744 | 0.92 | SCD (0.42) | SCDPPARGNR4A2MTNR1AMTNR1B | |
| SCHEMBL5738604 | 0.88 | MAOB (0.40) | MAOBSCDMEN1NPC1MAPT | |
| SCHEMBL5738353 | 0.83 | ALDH1A1 (0.42) | SCDPPARGMEN1NPC1TP53 | |
| SCHEMBL5767326 | 0.78 | CCR1 (0.39) | MEN1LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7005265 | 0.76 | MAPT (0.44) | MAOBMAPTKMT2APOLB | |
| SCHEMBL5736875 | 0.75 | MAPT (0.41) | SCDUSP2MEN1NPC1LMNA | |
| SCHEMBL5737188 | 0.75 | GPR35 (0.41) | — | |
| SCHEMBL7003912 | 0.71 | LTB4R2 (0.43) | SCDPPARGUSP2MEN1NPC1 | |
| SCHEMBL6092537 | 0.69 | PPARG (0.59) | MAOBPPARGEDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1646624-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | Biolipox AB (SE) | 2006-04-19 | — | — | EP | disclosed |
| WO-2005005415-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2005-01-20 | — | — | WO | disclosed |