Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CACNA1G | O43497 | 3/20 | 0.35 |
| ▸ | CACNA1H | O95180 | 3/20 | 0.35 |
| ▸ | CACNA1I | Q9P0X4 | 3/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | SLC34A2 | O95436 | 2/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | ACACA | Q13085 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 2/20 | 0.32 |
| ▸ | ACHE | P22303 | 2/20 | 0.32 |
| ▸ | FABP4 | P15090 | 2/20 | 0.32 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.32 |
| ▸ | F9 | P00740 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6656583 | 0.88 | ACHE (0.35) | SLC34A2FAAHBCHEACHEALDH1A1 | |
| SCHEMBL5741841 | 0.84 | FABP4 (0.33) | KIF11PDE4BPDE4DSLC34A2FABP4 | |
| SCHEMBL6510139 | 0.83 | KMT2A (0.41) | LMNAHSD17B10CACNA1GCACNA1HCACNA1I | |
| SCHEMBL5740952 | 0.81 | KIF11 (0.41) | LMNAHSD17B10CACNA1GCACNA1HCACNA1I | |
| SCHEMBL5741790 | 0.77 | KIF11 (0.31) | KIF11 | |
| SCHEMBL5739761 | 0.75 | ACHE (0.37) | LMNAHSD17B10KIF11SLC34A2ACHE | |
| SCHEMBL5741839 | 0.74 | RXRA (0.37) | KIF11PDE4BPDE4DSLC34A2FABP4 | |
| SCHEMBL5740408 | 0.74 | SLC34A2 (0.35) | CACNA1GCACNA1HCACNA1IKIF11PDE4B | |
| SCHEMBL5740285 | 0.73 | CYP26A1 (0.40) | HSD17B10CACNA1GCACNA1HCACNA1IKIF11 | |
| SCHEMBL6508440 | 0.73 | KIF11 (0.34) | KIF11PDE4BPDE4DSLC34A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1406891-B1 | THIOCHROMENONES USED TO COMBAT PAINFUL CONDITIONS AND NEURODEGENERATIVE DISEASES | BAYER HEALTHCARE AG (DE) | 2006-03-22 | — | — | EP | disclosed |