Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 5/20 | 0.33 |
| ▸ | FABP5 | Q01469 | 5/20 | 0.33 |
| ▸ | SLC34A2 | O95436 | 3/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.32 |
| ▸ | RAB7A | P51149 | 1/20 | 0.31 |
| ▸ | PRNP | P04156 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.30 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5742423 | 0.84 | LMNA (0.35) | FABP4FABP5SLC34A2KIF11PDE4B | |
| SCHEMBL6656583 | 0.83 | ACHE (0.35) | SLC34A2 | |
| SCHEMBL5741839 | 0.82 | RXRA (0.37) | FABP4FABP5SLC34A2KIF11PDE4B | |
| SCHEMBL5741790 | 0.81 | KIF11 (0.31) | KIF11 | |
| SCHEMBL6689646 | 0.81 | PTGS2 (0.39) | MAPK1HTT | |
| SCHEMBL5740952 | 0.81 | KIF11 (0.41) | SLC34A2KIF11TSHRMAPK1NPSR1 | |
| SCHEMBL5739761 | 0.80 | ACHE (0.37) | SLC34A2KIF11TSHRMAPK1NPSR1 | |
| SCHEMBL5740682 | 0.80 | PTGS2 (0.38) | TSHRMAPK1HTTNPSR1 | |
| SCHEMBL5740285 | 0.80 | CYP26A1 (0.40) | FABP4FABP5SLC34A2KIF11TSHR | |
| SCHEMBL5740233 | 0.78 | LIMK1 (0.40) | FABP4FABP5KIF11PDE4BPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1406891-B1 | THIOCHROMENONES USED TO COMBAT PAINFUL CONDITIONS AND NEURODEGENERATIVE DISEASES | BAYER HEALTHCARE AG (DE) | 2006-03-22 | — | — | EP | disclosed |
| EP-1406891-A1 | THIOCHROMENONES USED TO COMBAT PAINFUL CONDITIONS AND NEURODEGENERATIVE DISEASES | Bayer HealthCare AG (DE) | 2004-04-14 | — | — | EP | disclosed |
| WO-2003053955-A1 | THIOCHROMENONES USED TO COMBAT PAINFUL CONDITIONS AND NEURODEGENERATIVE DISEASES | BAYER HEALTHCARE AG (DE) | 2003-07-03 | — | — | WO | disclosed |