Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 9/20 | 0.35 |
| ▸ | BCHE | P06276 | 7/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SLC34A2 | O95436 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5742423 | 0.88 | LMNA (0.35) | ACHEBCHEMEN1KMT2AALDH1A1 | |
| SCHEMBL6504028 | 0.83 | MAPK14 (0.41) | MEN1KMT2ACNR1CNR2ALDH1A1 | |
| SCHEMBL5741841 | 0.83 | FABP4 (0.33) | SLC34A2 | |
| SCHEMBL5739761 | 0.82 | ACHE (0.37) | ACHEMEN1KMT2AALDH1A1SLC34A2 | |
| SCHEMBL5741790 | 0.76 | KIF11 (0.31) | — | |
| SCHEMBL5740952 | 0.75 | KIF11 (0.41) | ACHEBCHEMEN1KMT2AALDH1A1 | |
| SCHEMBL5741839 | 0.73 | RXRA (0.37) | SLC34A2 | |
| SCHEMBL5740408 | 0.73 | SLC34A2 (0.35) | SLC34A2 | |
| SCHEMBL6507664 | 0.73 | KIF11 (0.40) | — | |
| SCHEMBL6510139 | 0.73 | KMT2A (0.41) | MEN1KMT2ACNR2SLC34A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1406891-A1 | THIOCHROMENONES USED TO COMBAT PAINFUL CONDITIONS AND NEURODEGENERATIVE DISEASES | Bayer HealthCare AG (DE) | 2004-04-14 | — | — | EP | disclosed |
| WO-2003053955-A1 | THIOCHROMENONES USED TO COMBAT PAINFUL CONDITIONS AND NEURODEGENERATIVE DISEASES | BAYER HEALTHCARE AG (DE) | 2003-07-03 | — | — | WO | disclosed |