SCHEMBL5741790

SCHEMBL5741790

CN(CC(F)(F)F)C(=O)Oc1ccc2c(=O)c3c(sc2c1)CC(C)(C)CC3

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 1/20 0.31
PDK2 Q15119 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6529416 0.84 PDK2 (0.36) KIF11PDK2
SCHEMBL5741841 0.81 FABP4 (0.33) KIF11
SCHEMBL5740952 0.79 KIF11 (0.41) KIF11
SCHEMBL5739761 0.79 ACHE (0.37) KIF11
SCHEMBL5742423 0.77 LMNA (0.35) KIF11
SCHEMBL6656583 0.76 ACHE (0.35)
SCHEMBL5741781 0.72 KIF11 (0.32) KIF11
SCHEMBL5740408 0.72 SLC34A2 (0.35) KIF11
SCHEMBL5741839 0.72 RXRA (0.37) KIF11
SCHEMBL5740285 0.71 CYP26A1 (0.40) KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1406891-B1 THIOCHROMENONES USED TO COMBAT PAINFUL CONDITIONS AND NEURODEGENERATIVE DISEASES BAYER HEALTHCARE AG (DE) 2006-03-22 EP disclosed