Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5249555 | 0.98 | ALDH1A1 (0.37) | ALDH1A1GPR55HSP90AA1HSP90AB1POLB | |
| Hydrochloric Acid SCHEMBL5249550 | 0.97 | ALDH1A1 (0.36) | ALDH1A1GPR55HSP90AA1HSP90AB1POLB | |
| SCHEMBL5759783 | 0.84 | NR1I2 (0.33) | ALDH1A1POLBMAPTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5754089 | 0.82 | NR1I2 (0.33) | ALDH1A1POLBMAPTSMN1; SMN2 | |
| SCHEMBL5756540 | 0.82 | ALDH1A1 (0.35) | ALDH1A1POLBMAPTGAAKMT2A | |
| SCHEMBL5761337 | 0.82 | ALDH1A1 (0.35) | ALDH1A1POLBMAPTGAAKMT2A | |
| SCHEMBL5759411 | 0.79 | ADRB2 (0.43) | ALDH1A1HSP90AA1HSP90AB1 | |
| SCHEMBL5755967 | 0.74 | PIK3CA (0.42) | ALDH1A1HSP90AA1HSP90AB1POLBPIK3CD | |
| SCHEMBL16040071 | 0.67 | MAPT (0.49) | ALDH1A1POLBPIK3CAMAPTGAA | |
| SCHEMBL5755278 | 0.67 | L3MBTL1 (0.41) | ALDH1A1HSP90AA1HSP90AB1PIK3CDPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 123 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11458083-B2 | Cosmetic and/or dermatological composition containing a merocyanine derivative comprising specific polar groups consisting of hydroxyl- and ether-functionalities | L'OREAL (FR) | 2022-10-04 | — | — | US | disclosed |
| EP-1919443-B1 | STABILIZATION OF BODY-CARE AND HOUSEHOLD PRODUCTS AGAINST DEGRADATION BY UV RADIATION USING MEROCYANINE DERIVATIVES | BASF SE (DE) | 2020-06-10 | — | — | EP | disclosed |
| EP-2435017-B1 | BENZYLIDENE MALONATES | BASF SE (DE) | 2019-10-23 | — | — | EP | disclosed |
| EP-3453379-A2 | MICROPIGMENT MIXTURES | Ciba Holding Inc. (CH) | 2019-03-13 | — | — | EP | disclosed |
| EP-1469819-B1 | MICROPIGMENT MIXTURES | CIBA HOLDING INC (CH) | 2019-01-09 | — | — | EP | disclosed |
| US-10098849-B2 | Anti-radical agents | BASF SE (DE) | 2018-10-16 | — | — | US | disclosed |
| EP-2162113-B1 | WATER BASED CONCENTRATED PRODUCT FORMS OF OIL-SOLUBLE ORGANIC UV ABSORBERS | BASF SE (DE) | 2017-08-09 | — | — | EP | disclosed |
| US-9707417-B2 | Use of benzotropolone derivatives as UV absorbers and antioxidants and their use in sunscreens and/or cosmetic compositions | BASF SE (DE) | 2017-07-18 | — | — | US | disclosed |
| US-9663442-B2 | Stabilization of household, body-care and food products by using benzotropolone containing plant extracts and/or related benzotropolone derivatives | BASF SE (DE) | 2017-05-30 | — | — | US | disclosed |
| US-9550730-B2 | Merocyanine derivatives | BASF SE (DE) | 2017-01-24 | — | — | US | disclosed |
| WO-2003070207-A1 | METHOD OF COLOURING KERATIN-CONTAINING FIBRES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2003-08-28 | — | — | WO | disclosed |
| WO-2003060015-A1 | YELLOW CATIONIC DYES FOR DYING OF ORGANIC MATERIAL | CIBA SPECIALITY CHEMICALS HOLDING INC. (CH) | 2003-07-24 | — | — | WO | disclosed |
| WO-2003032939-A1 | METHOD OF COLOURING KERATIN-CONTAINING FIBRES USING DIAZONIUM SALTS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2003-04-24 | — | — | WO | disclosed |
| WO-2003029359-A1 | CATIONIC REACTIVE DYES | CIBA SPECIALTY CHEMICALS HOLDINGS INC. (CH) | 2003-04-10 | — | — | WO | disclosed |
| CN-1404508-A | Gel-form composition | SHISEIDO CO LTD (JP) | 2003-03-19 | — | — | CN | disclosed |
| US-6476024-B1 | Pyridazine derivatives and related composition | SHISEIDO CO. LTD. (JP) | 2002-11-05 | — | — | US | disclosed |
| US-6395896-B2 | REACTING AT LEAST 10 WT % OF 4,5-DICHLORO-3-HYDROXYPYRIDAZINE OR 4,5-DIBROMO-3-HYDROXYPYRIDAZINE OR A MIXTURE WITH ATLEAST 20 VOL% OF MORPHOLINE IN A REACTION SOLUTION AT 70 DEGREE C. OR HIGHER; ULTRAVIOLET ABSORBENTS AND PHOTOSTABILIZERS | SHISEIDO CO., LTD. (JP) | 2002-05-28 | — | — | US | disclosed |
| CN-1308068-A | Pyridazine derivative and its preparation and composite containing the derivative | SHISEI CO LTD (JP) | 2001-08-15 | — | — | CN | disclosed |
| US-20010012841-A1 | Pyridazine derivatives, manufacturing method and related composition | SHISEIDO CO., LTD. (JP) | 2001-08-09 | — | — | US | disclosed |
| EP-1108712-A1 | 3-Hydroxy-4,5-bis(morpholin-1-yl)pyridazine as UV absorber | SHISEIDO COMPANY LIMITED (JP) | 2001-06-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11458083-B2 | Cosmetic and/or dermatological composition containing a merocyanine derivative comprising specific polar groups consisting of hydroxyl- and ether-functionalities | KRT18, LAGE3, TYR | ALDH1A1 1018/4885GPR55 1645/4885HSP90AA1 2291/4885 |
| US-20010012841-A1 | Pyridazine derivatives, manufacturing method and related composition | CYP4F12, CYP4Z1, CYP3A5 | ALDH1A1 267/4885GPR55 548/4885HSP90AA1 3225/4885 |
| US-10098849-B2 | Anti-radical agents | NOS3, GSTO1, TXN2 | ALDH1A1 881/4885GPR55 4230/4885HSP90AA1 1798/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.