Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 5/20 | 0.39 |
| ▸ | FYN | P06241 | 3/20 | 0.39 |
| ▸ | FLT3 | P36888 | 2/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5764442 | 0.91 | HPGD (0.44) | ALDH1A1HSD17B10TSHRNPSR1POLB | |
| SCHEMBL5764324 | 0.89 | ALDH1A1 (0.47) | ALDH1A1HSD17B10TSHRNPSR1POLB | |
| SCHEMBL5764441 | 0.86 | ALDH1A1 (0.39) | ALDH1A1HSD17B10TSHRNPSR1MAPT | |
| SCHEMBL5764583 | 0.85 | ALDH1A1 (0.36) | ALDH1A1HSD17B10TSHRNPSR1POLB | |
| SCHEMBL5764846 | 0.84 | GPR4 (0.44) | ALDH1A1TSHRNPSR1MAPTHPGD | |
| SCHEMBL5764508 | 0.77 | PPARG (0.40) | ALDH1A1HSD17B10TSHRNPSR1POLB | |
| SCHEMBL5763739 | 0.76 | MEN1 (0.52) | ALDH1A1HSD17B10TSHRNPSR1POLB | |
| SCHEMBL5765021 | 0.71 | GAA (0.38) | ALDH1A1HSD17B10NPSR1POLBMAPT | |
| SCHEMBL31511378 | 0.68 | DCTPP1 (0.41) | ALDH1A1MAPTSRCABL1MEN1 | |
| SCHEMBL5475245 | 0.66 | L3MBTL1 (0.51) | ALDH1A1HSD17B10POLBMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091738-B1 | BICYCLIC sPLA 2 INHIBITORS | LILLY CO ELI (US) | 2006-12-06 | — | — | EP | disclosed |
| US-6384041-B1 | ANTIINFLAMMATORY AGENT, TREATMENT OF SHOCK AND ENZYME INHIBITORS | ELI LILLY AND COMPANY | 2002-05-07 | — | — | US | disclosed |