Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.62 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | ACHE | P22303 | 4/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.40 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.38 |
| ▸ | TTPA | P49638 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30267482 | 1.00 | PTGS1 (0.62) | PTGS1PTGS2CYP1A2CYP3A4TSHR | |
| SCHEMBL20764429 | 1.00 | PTGS1 (0.62) | PTGS1PTGS2CYP1A2CYP3A4TSHR | |
| SCHEMBL20764451 | 1.00 | PTGS1 (0.62) | PTGS1PTGS2CYP1A2CYP3A4TSHR | |
| SCHEMBL29500472 | 1.00 | PTGS1 (0.62) | PTGS1PTGS2CYP1A2CYP3A4TSHR | |
| SCHEMBL30534604 | 0.89 | CYP3A4 (0.67) | PTGS1PTGS2CYP1A2CYP3A4TSHR | |
| SCHEMBL10367354 | 0.89 | CYP3A4 (0.67) | PTGS1PTGS2CYP1A2CYP3A4TSHR | |
| SCHEMBL2059278 | 0.88 | CYP3A4 (0.65) | PTGS1PTGS2CYP1A2CYP3A4TSHR | |
| SCHEMBL5770041 | 0.86 | PTGS1 (0.64) | PTGS1PTGS2CYP1A2CYP3A4TSHR | |
| SCHEMBL20764448 | 0.86 | PTGS1 (0.64) | PTGS1PTGS2CYP1A2CYP3A4TSHR | |
| SCHEMBL2059305 | 0.86 | PTGS1 (0.64) | PTGS1PTGS2CYP1A2CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 109 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250177384-A1 | CHROMANOL COMPOUNDS FOR TREATMENT OR PROPHYLAXIS OF AGEING-ASSOCIATED DISORDERS | SULFATEQ B.V. (NL) | 2025-06-05 | — | — | US | claimed |
| US-12156862-B2 | Medicaments for the treatment of vasoconstriction related diseases or disorders | SULFATEQ B.V. (NL) | 2024-12-03 | — | — | US | claimed |
| CN-118742301-A | Chromanol compounds for use in the treatment or prevention of aging-related disorders | 萨尔法泰克有限公司 | 2024-10-01 | — | — | CN | claimed |
| US-20230330060-A1 | COMPOUNDS FOR TREATMENT OF HEART FAILURE | SULFATEQ B.V. (NL) | 2023-10-19 | — | — | US | claimed |
| WO-2023163596-A1 | CHROMANOL COMPOUNDS FOR TREATMENT OR PROPHYLAXIS OF AGEING-ASSOCIATED DISORDERS | SULFATEQ B.V. (NL) | 2023-08-31 | — | — | WO | claimed |
| EP-4213825-A1 | CHROMANOL COMPOUNDS FOR TREATMENT OF HEART FAILURE | Sulfateq B.V. (NL) | 2023-07-26 | — | — | EP | claimed |
| EP-3388426-B1 | COMPOUNDS FOR PROTECTION OF CELLS | SULFATEQ BV (NL) | 2023-07-05 | — | — | EP | claimed |
| CN-116322661-A | Chromanol compounds for the treatment of heart failure | 萨尔法泰克有限公司 | 2023-06-23 | — | — | CN | claimed |
| EP-4157261-A1 | CHROMANOL, QUINONE OR HYDROQUINONE COMPOUNDS FOR TREATMENT OF SEPSIS | Sulfateq B.V. (NL) | 2023-04-05 | — | — | EP | claimed |
| EP-4072550-A1 | COMPOUNDS FOR TREATMENT OF ALZHEIMER'S DISEASE | Sulfateq B.V. (NL) | 2022-10-19 | — | — | EP | claimed |
| EP-3157518-A1 | 6-HYDROXY-2,5,7,8-TETRAMETHYLCHROMAN-COMPOUNDS FOR THE TREATMENT OF CHRONIC OBSTRUCTIVE AIRWAY DISEASES | Sulfateq B.V. (NL) | 2017-04-26 | — | — | EP | claimed |
| US-20160324823-A1 | TREATMENT OF MITOCHONDRIAL DISEASES | BIOELECTRON TECHNOLOGY CORPORATION | 2016-11-10 | — | — | US | claimed |
| WO-2015193365-A1 | 6-HYDROXY-2,5,7,8-TETRAMETHYLCHROMAN-COMPOUNDS FOR THE TREATMENT OF CHRONIC OBSTRUCTIVE AIRWAY DISEASES | SULFATEQ B.V. (NL) | 2015-12-23 | — | — | WO | claimed |
| US-20130267538-A1 | TREATMENT OF MITOCHONDRIAL DISEASES | GALILEO PHARMACEUTICALS INC. | 2013-10-10 | — | — | US | claimed |
| WO-2005032544-A1 | TREATMENT OF MITOCHONDRIAL DISEASES | GALILEO PHARMACEUTICALS, INC. (US) | 2005-04-14 | — | — | WO | claimed |
| US-20050065099-A1 | Alzheimer's disease; Parkinson's disease; brain disorders; antiepileptic agents; amyotrophic lateral sclerosis; vision defects | EDISON PHARMACEUTICALS, INC. | 2005-03-24 | — | — | US | claimed |
| EP-0487510-A1 | Pharmaceutically active amines | THE UPJOHN COMPANY (US) | 1992-05-27 | — | — | EP | claimed |
| EP-0358676-A1 | PHARMACEUTICALLY ACTIVE AMINES | THE UPJOHN COMPANY (US) | 1990-03-21 | — | — | EP | claimed |
| EP-0293078-A1 | Pharmaceutically active amines | THE UPJOHN COMPANY (US) | 1988-11-30 | — | — | EP | claimed |
| WO-1988008424-A1 | PHARMACEUTICALLY ACTIVE AMINES | THE UPJOHN COMPANY (US) | 1988-11-03 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250177384-A1 | CHROMANOL COMPOUNDS FOR TREATMENT OR PROPHYLAXIS OF AGEING-ASSOCIATED DISORDERS | SULT2A1, SULT1A1, CYP2A13 | PTGS1 159/4885PTGS2 172/4885CYP1A2 30/4885 |
| US-20050065099-A1 | Alzheimer's disease; Parkinson's disease; brain disorders; antiepileptic agents; amyotrophic lateral sclerosis; vision defects | CLN6, LDHA, NLN | PTGS1 3200/4885PTGS2 3398/4885CYP1A2 2091/4885 |
| US-20160324823-A1 | TREATMENT OF MITOCHONDRIAL DISEASES | NLN, FH, MFN2 | PTGS1 2790/4885PTGS2 2651/4885CYP1A2 2253/4885 |
| US-20130267538-A1 | TREATMENT OF MITOCHONDRIAL DISEASES | NLN, FH, MFN2 | PTGS1 2790/4885PTGS2 2651/4885CYP1A2 2253/4885 |
| US-20230330060-A1 | COMPOUNDS FOR TREATMENT OF HEART FAILURE | SQOR, SDHA, NDUFV2 | PTGS1 550/4885PTGS2 454/4885CYP1A2 226/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.