Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5773884 | 0.80 | HDAC3 (0.41) | FAAHCES1 | |
| SCHEMBL3871979 | 0.71 | FAAH (0.45) | FAAHCES1 | |
| SCHEMBL5774900 | 0.66 | FAAH (0.36) | FAAHCES1 | |
| SCHEMBL4066120 | 0.60 | CTSL (0.37) | — | |
| SCHEMBL9911657 | 0.60 | ALDH1A1 (0.56) | FAAHCES1 | |
| SCHEMBL30301352 | 0.57 | CES1 (0.53) | FAAHCES1 | |
| SCHEMBL30301351 | 0.57 | CES1 (0.53) | FAAHCES1 | |
| SCHEMBL3869379 | 0.57 | CTSC (0.46) | — | |
| SCHEMBL30716058 | 0.56 | HPGD (0.61) | — | |
| SCHEMBL363265 | 0.56 | KDM4E (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1682524-A1 | NOVEL KETO-OXADIAZOLE DERIVATIVES AS CATHEPSIN INHIBITORS | Aventis Pharmaceuticals, Inc. (US) | 2006-07-26 | — | — | EP | claimed |
| WO-2005040142-A1 | NOVEL KETO-OXADIAZOLE DERIVATIVES AS CATHEPSIN INHIBITORS | AVENTIS PHARMACEUTICALS INC. (US) | 2005-05-06 | — | — | WO | claimed |
| WO-2005040142-A9 | NOVEL KETO-OXADIAZOLE DERIVATIVES AS CATHEPSIN INHIBITORS | AVENTIS PHARMA INC (US) | 2005-06-09 | — | — | WO | disclosed |