Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 17/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | SPR | P35270 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5774732 | 0.77 | KDM4E (0.43) | CCR2KDM4EBRD4ALDH1A1POLB | |
| SCHEMBL2186733 | 0.75 | KDM4E (0.48) | CCR2KDM4EBRD4ALDH1A1POLB | |
| SCHEMBL2188126 | 0.74 | ALDH1A1 (0.50) | CCR2KDM4EBRD4ALDH1A1POLB | |
| SCHEMBL2188470 | 0.73 | KDM4E (0.51) | CCR2KDM4EBRD4ALDH1A1POLB | |
| SCHEMBL27698609 | 0.73 | KMT2A (0.45) | CCR2KDM4EBRD4ALDH1A1POLB | |
| SCHEMBL2213735 | 0.72 | KDM4E (0.52) | KDM4EBRD4ALDH1A1POLBCREBBP | |
| SCHEMBL2186025 | 0.71 | KDM4E (0.46) | CCR2KDM4EBRD4ALDH1A1POLB | |
| SCHEMBL27698607 | 0.71 | KMT2A (0.46) | CCR2KDM4EBRD4ALDH1A1POLB | |
| SCHEMBL2187329 | 0.69 | SLC6A4 (0.45) | KDM4EBRD4ALDH1A1POLBCREBBP | |
| SCHEMBL2185602 | 0.67 | KDM4E (0.45) | CCR2KDM4EBRD4ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1637529-A1 | Novel piperidin-4-yl-thiazole-carboxamide analogues as inhibitors of T-cell proliferation and uses thereof | 4SC AG (DE) | 2006-03-22 | — | — | EP | disclosed |