Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | SPR | P35270 | 9/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | IDE | P14735 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2187334 | 0.84 | KDM4E (0.39) | SPRKDM4EBRD4ALDH1A1POLB | |
| SCHEMBL5774732 | 0.83 | KDM4E (0.43) | SPRKDM4EBRD4ALDH1A1POLB | |
| SCHEMBL2188126 | 0.78 | ALDH1A1 (0.50) | SPRKDM4EBRD4ALDH1A1POLB | |
| SCHEMBL2186733 | 0.76 | KDM4E (0.48) | SPRKDM4EBRD4ALDH1A1POLB | |
| SCHEMBL2188470 | 0.73 | KDM4E (0.51) | SPRKDM4EBRD4ALDH1A1POLB | |
| SCHEMBL2213735 | 0.72 | KDM4E (0.52) | SPRKDM4EBRD4ALDH1A1POLB | |
| SCHEMBL2186025 | 0.71 | KDM4E (0.46) | SPRKDM4EBRD4ALDH1A1POLB | |
| SCHEMBL2187684 | 0.71 | HSD11B1 (0.48) | SLC6A4SPRKDM4EBRD4ALDH1A1 | |
| SCHEMBL27698607 | 0.69 | KMT2A (0.46) | SPRKDM4EBRD4ALDH1A1POLB | |
| SCHEMBL27698609 | 0.69 | KMT2A (0.45) | SPRKDM4EBRD4ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2343293-A1 | NOVEL PIPERIDIN-4-YL-THIAZOLE-CARBOXAMIDE ANALOGUES AS INHIBITORS OF T-CELL PROLIFERATION AND USES THEREOF | 4SC AG (DE) | 2011-07-13 | — | — | EP | disclosed |