Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | HTR7 | P34969 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HPN | P05981 | 1/20 | 0.48 |
| ▸ | ENPP2 | Q13822 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1126076 | 0.82 | MAPT (0.60) | MAPTKDM4EMEN1KMT2AHTR7 | |
| SCHEMBL31232720 | 0.80 | HTR7 (0.56) | MAPTKDM4EMEN1KMT2AHTR7 | |
| SCHEMBL520396 | 0.80 | HTR7 (0.56) | MAPTKDM4EMEN1KMT2AHTR7 | |
| SCHEMBL5165090 | 0.80 | MAPT (0.54) | MAPTKDM4EMEN1KMT2AHTR7 | |
| SCHEMBL2627249 | 0.79 | MAPT (0.69) | MAPTKDM4EMEN1KMT2AHTR7 | |
| SCHEMBL2658558 | 0.78 | POLB (0.56) | MAPTKDM4EMEN1KMT2AHTR7 | |
| Hydrochloric Acid SCHEMBL31232759 | 0.78 | HTR7 (0.58) | MAPTKDM4EMEN1KMT2AHTR7 | |
| SCHEMBL2659435 | 0.78 | L3MBTL1 (0.61) | MAPTKDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL2658565 | 0.78 | POLB (0.56) | MAPTKDM4EMEN1KMT2AHTR7 | |
| SCHEMBL533010 | 0.78 | MAPT (0.66) | MAPTKDM4EMEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1194410-B1 | BENZIMIDAZOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THESE COMPOUNDS | NEUROSEARCH AS (DK) | 2006-01-18 | — | — | EP | disclosed |
| US-6936613-B2 | Benzimidazole derivatives and pharmaceutical compositions comprising these compounds | NEUROSEARCH A/S (DK) | 2005-08-30 | — | — | US | disclosed |
| CN-1167686-C | Novel benzimidazole derivatives and pharmaceutical compsns. comprising these compounds | О | 2004-09-22 | — | — | CN | disclosed |
| US-20040097570-A1 | Novel benzimidazole derivatives and pharmaceutical compositions comprising these compounds | NEUROSEARCH A/S | 2004-05-20 | — | — | US | disclosed |
| CN-1356987-A | Novel benzimidazole derivatives and pharmaceutical compsns. comprising these compounds | NEUROSEARCH AS (DK) | 2002-07-03 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040097570-A1 | Novel benzimidazole derivatives and pharmaceutical compositions comprising these compounds | GABRA1, GABRA2, GABRA4 | MAPT 906/4885KDM4E 851/4885MEN1 4632/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.