Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.59 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.50 |
| ▸ | HTR1A | P08908 | 2/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | LTA4H | P09960 | 2/20 | 0.48 |
| ▸ | TACR1 | P25103 | 2/20 | 0.47 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL6957258 | 0.88 | HCAR2 (0.48) | SIGMAR1SLC6A2SLC6A4HTR1ASLC6A3 | |
| Fumaric Acid SCHEMBL6957253 | 0.88 | HCAR2 (0.48) | SIGMAR1SLC6A2SLC6A4HTR1ASLC6A3 | |
| SCHEMBL30128338 | 0.83 | LTA4H (0.56) | SIGMAR1SLC6A3TSHRLTA4H | |
| SCHEMBL4663018 | 0.83 | LTA4H (0.60) | SIGMAR1SLC6A3TSHRLTA4H | |
| SCHEMBL6121049 | 0.83 | LTA4H (0.65) | SIGMAR1SLC6A2SLC6A4HTR1ASLC6A3 | |
| SCHEMBL7301909 | 0.81 | LMNA (0.59) | SIGMAR1SLC6A3TSHRLTA4H | |
| SCHEMBL8243447 | 0.80 | LTA4H (0.61) | SIGMAR1SLC6A2SLC6A4HTR1ASLC6A3 | |
| SCHEMBL28565386 | 0.80 | SIGMAR1 (0.64) | SIGMAR1SLC6A2SLC6A4SLC6A3LTA4H | |
| SCHEMBL4438692 | 0.79 | POLB (0.53) | SIGMAR1TSHRLTA4HEGFRMEN1 | |
| SCHEMBL30997860 | 0.77 | LTA4H (0.57) | SIGMAR1SLC6A2SLC6A4HTR1ASLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104046246-A | Chemical Mechanical Planarization for Tungsten-Containing Substrates | AIR PROD & CHEM | 2014-09-17 | — | — | CN | disclosed |
| EP-1643998-A1 | DUAL NK1/NK3 ANTAGONISTS FOR TREATING SCHIZOPHRENIA | F. HOFFMANN-LA ROCHE AG (CH) | 2006-04-12 | — | — | EP | disclosed |
| WO-2005002577-A1 | DUAL NK1/NK3 ANTAGONISTS FOR TREATING SCHIZOPHRENIA | F. HOFFMANN-LA ROCHE AG (CH) | 2005-01-13 | — | — | WO | disclosed |
| CN-1365359-A | Benzofurylpiperazines and benzofurylhomopiperazines: serotonin agonists | LILLY CO ELI (US) | 2002-08-21 | — | — | CN | disclosed |
| EP-1204654-A1 | BENZOFURYLPIPERAZINES AND BENZOFURYLHOMOPIPERAZINES: SEROTONIN AGONISTS | ELI LILLY AND COMPANY (US) | 2002-05-15 | — | — | EP | disclosed |
| WO-2001009111-A1 | BENZOFURYLPIPERAZINES AND BENZOFURYLHOMOPIPERAZINES: SEROTONIN AGONISTS | ELI LILLY AND COMPANY (US) | 2001-02-08 | — | — | WO | disclosed |