Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | LTA4H | P09960 | 3/20 | 0.58 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4663018 | 0.98 | LTA4H (0.60) | LMNALTA4HSIGMAR1TSHRHRH3 | |
| SCHEMBL30128338 | 0.94 | LTA4H (0.56) | LMNALTA4HSIGMAR1TSHRHRH3 | |
| SCHEMBL4438692 | 0.81 | POLB (0.53) | LMNALTA4HSIGMAR1TSHRHSD17B10 | |
| SCHEMBL5788869 | 0.81 | SIGMAR1 (0.59) | LTA4HSIGMAR1TSHRSLC6A3 | |
| SCHEMBL6393260 | 0.81 | LTA4H (0.84) | LMNALTA4HSIGMAR1HRH3SLC6A3 | |
| SCHEMBL13992754 | 0.80 | TSHR (0.47) | LMNALTA4HSIGMAR1TSHR | |
| SCHEMBL29447351 | 0.79 | LTA4H (0.87) | LTA4HSIGMAR1HRH3SLC6A3RAB9A | |
| Cyclohexane SCHEMBL8149682 | 0.79 | TSHR (0.83) | LMNALTA4HTSHR | |
| SCHEMBL5188945 | 0.78 | TEAD3 (0.52) | LMNATSHRSMN1; SMN2 | |
| SCHEMBL22440218 | 0.77 | LTA4H (0.77) | LTA4HSIGMAR1HRH3SLC6A3RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115697989-A | Tropomyosin Receptor Kinase (TRK) degrading compounds and methods of use | 上海睿跃生物科技有限公司 | 2023-02-03 | — | — | CN | disclosed |
| US-5169855-A | PIPERIDINE ETHER DERIVATIVES AS PSYCHOTROPIC DRUGS OR PLANT FUNGICIDES | DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1992-12-08 | — | — | US | disclosed |
| EP-0449187-A2 | Piperidin ether derivatives as psychotropic drugs or plant fungicides | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1991-10-02 | — | — | EP | disclosed |