Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | ALPL | P05186 | 1/20 | 0.34 |
| ▸ | RPA1 | P27694 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4242626 | 0.81 | CES2 (0.43) | KMT2AMEN1AKR1B1ALDH1A1HTT | |
| SCHEMBL5796336 | 0.77 | CES2 (0.41) | KMT2AMEN1AKR1B1ALDH1A1HTT | |
| SCHEMBL5798526 | 0.75 | AKR1B1 (0.48) | KMT2AMEN1AKR1B1ALDH1A1CES2 | |
| SCHEMBL3169587 | 0.71 | AKR1B1 (0.46) | KMT2AMEN1AKR1B1ALDH1A1HTT | |
| SCHEMBL2534850 | 0.70 | CES2 (0.48) | ALDH1A1HTTCES2CES1PTPN1 | |
| SCHEMBL8905938 | 0.70 | MEN1 (0.38) | KMT2AMEN1AKR1B1ALDH1A1HTT | |
| SCHEMBL3364624 | 0.67 | GSK3B (0.61) | KMT2AMEN1ALDH1A1CES2CES1 | |
| SCHEMBL4470958 | 0.67 | LTA4H (0.55) | KMT2AMEN1L3MBTL1CES2CES1 | |
| SCHEMBL4245618 | 0.67 | RAB9A (0.51) | KMT2AMEN1AKR1B1ALDH1A1CES2 | |
| SCHEMBL30410204 | 0.67 | KMT2A (0.38) | KMT2AALDH1A1CES2CES1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006038734-A1 | PYRIDAZINONE DERIVATIVES CYTOKINES INHIBITORS | ASTELLAS PHARMA INC. (JP) | 2006-04-13 | — | — | WO | disclosed |