Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5794528 | 0.88 | PKM (0.53) | ALDH1A1CYP2C9CYP2C19KMT2AMEN1 | |
| SCHEMBL5797968 | 0.87 | KMT2A (0.68) | ALDH1A1CYP2C9CYP2C19KMT2AMEN1 | |
| SCHEMBL5811010 | 0.81 | KMT2A (0.61) | ALDH1A1CYP2C9CYP2C19KMT2AMEN1 | |
| SCHEMBL5794952 | 0.80 | HSD11B1 (0.53) | ALDH1A1CYP2C9CYP2C19KMT2AMEN1 | |
| SCHEMBL5693072 | 0.78 | HSD11B1 (0.76) | ALDH1A1CYP2C9CYP2C19KMT2AMEN1 | |
| SCHEMBL5806893 | 0.78 | CDK5 (0.49) | ALDH1A1CYP2C9CYP2C19KMT2AMEN1 | |
| SCHEMBL30416934 | 0.77 | CTPS1 (0.57) | ALDH1A1CYP2C9CYP2C19KMT2AMEN1 | |
| SCHEMBL21381652 | 0.77 | CTPS1 (0.57) | ALDH1A1CYP2C9CYP2C19KMT2AMEN1 | |
| SCHEMBL5736794 | 0.76 | LMNA (0.44) | ALDH1A1CYP2C9CYP2C19KMT2AMEN1 | |
| SCHEMBL7044048 | 0.75 | LMNA (0.43) | ALDH1A1CYP2C9CYP2C19KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006050908-A1 | INHIBITORS OF 11ΒΕΤΑ-HYDROXY STEROID DEHYDROGENASE TYPE 1 (11BETA-HSD1) | EVOTEC AG (DE) | 2006-05-18 | — | — | WO | disclosed |