Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5798138 | 0.88 | ALDH1A1 (0.53) | PKMALDH1A1MEN1KMT2ACYP2C9 | |
| SCHEMBL5794917 | 0.87 | HDAC3 (0.51) | ALDH1A1MEN1KMT2AMAPK1FFAR4 | |
| SCHEMBL5797968 | 0.86 | KMT2A (0.68) | PKMALDH1A1MEN1KMT2ACYP2C9 | |
| SCHEMBL27650022 | 0.82 | PKM (0.78) | PKMALDH1A1MEN1KMT2ACYP2C9 | |
| SCHEMBL5811010 | 0.79 | KMT2A (0.61) | PKMALDH1A1MEN1KMT2ACYP2C9 | |
| SCHEMBL5794952 | 0.77 | HSD11B1 (0.53) | PKMALDH1A1MEN1KMT2ACYP2C9 | |
| SCHEMBL5693072 | 0.75 | HSD11B1 (0.76) | ALDH1A1MEN1KMT2ACYP2C9CYP2C19 | |
| SCHEMBL5806893 | 0.75 | CDK5 (0.49) | PKMALDH1A1MEN1KMT2ACYP2C9 | |
| SCHEMBL28538998 | 0.74 | KEAP1 (0.56) | ALDH1A1MEN1KMT2AMAPK1FFAR4 | |
| SCHEMBL21381652 | 0.74 | CTPS1 (0.57) | ALDH1A1MEN1KMT2ACYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006050908-A1 | INHIBITORS OF 11ΒΕΤΑ-HYDROXY STEROID DEHYDROGENASE TYPE 1 (11BETA-HSD1) | EVOTEC AG (DE) | 2006-05-18 | — | — | WO | disclosed |