Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | GSK3B | P49841 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5796130 | 0.82 | KMT2A (0.45) | ALDH1A1MAPTHPGDKDM4ETDP1 | |
| SCHEMBL6134151 | 0.77 | NNMT (0.45) | ALDH1A1RAB9ANPC1MAPTL3MBTL1 | |
| SCHEMBL6202557 | 0.74 | VNN1 (0.51) | ALDH1A1RAB9ANPC1MAPTL3MBTL1 | |
| SCHEMBL11636011 | 0.72 | KDM4E (0.55) | ALDH1A1RAB9ANPC1MAPTL3MBTL1 | |
| SCHEMBL1554856 | 0.71 | L3MBTL1 (0.53) | ALDH1A1RAB9ANPC1MAPTL3MBTL1 | |
| SCHEMBL31078157 | 0.71 | SLC6A3 (0.49) | ALDH1A1RAB9ANPC1MAPTL3MBTL1 | |
| SCHEMBL10796459 | 0.70 | RAB9A (0.49) | ALDH1A1RAB9ANPC1MAPTL3MBTL1 | |
| SCHEMBL31292392 | 0.70 | ALDH1A1 (0.46) | ALDH1A1RAB9ANPC1MAPTHPGD | |
| SCHEMBL24760727 | 0.70 | RAB9A (0.53) | ALDH1A1RAB9ANPC1MAPTL3MBTL1 | |
| SCHEMBL6011931 | 0.69 | RAB9A (0.75) | ALDH1A1RAB9ANPC1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006038734-A1 | PYRIDAZINONE DERIVATIVES CYTOKINES INHIBITORS | ASTELLAS PHARMA INC. (JP) | 2006-04-13 | — | — | WO | disclosed |