Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 6/20 | 0.42 |
| ▸ | CTSS | P25774 | 3/20 | 0.42 |
| ▸ | CTSL | P07711 | 2/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.35 |
| ▸ | PAK4 | O96013 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 2/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
| ▸ | PANK3 | Q9H999 | 2/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.33 |
| ▸ | CDC42BPB | Q9Y5S2 | 2/20 | 0.33 |
| ▸ | CDK8 | P49336 | 2/20 | 0.33 |
| ▸ | CCNC | P24863 | 1/20 | 0.33 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.33 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.33 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5806357 | 0.79 | FGFR4 (0.37) | CTSKCTSSCTSLCTSBPAK4 | |
| SCHEMBL5809045 | 0.76 | CTSK (0.45) | CTSKCTSSCTSLPAK4GPR119 | |
| SCHEMBL5791415 | 0.76 | CTSK (0.47) | CTSKCTSSCTSLCTSBHRH4 | |
| SCHEMBL5808749 | 0.73 | CACNA1G (0.37) | CTSKCTSSCTSLCTSBPAK4 | |
| SCHEMBL5792194 | 0.70 | CXCR3 (0.37) | PANK3 | |
| Trifluoroacetic Acid SCHEMBL5791860 | 0.68 | CTSS (0.36) | CTSKCTSSPAK4 | |
| SCHEMBL19116510 | 0.67 | SMN1; SMN2 (0.57) | CTSK | |
| SCHEMBL8270031 | 0.67 | CTSK (0.72) | CTSKCTSSCTSLCTSBABL1 | |
| SCHEMBL5794243 | 0.65 | CTSS (0.39) | CTSKCTSSCTSLCTSB | |
| SCHEMBL4137242 | 0.65 | HRH4 (0.50) | CTSKHRH4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006027211-A1 | 2,4-SUBSTITUTED PYRIMIDINES AS CYSTEINE PROTEASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2006-03-16 | — | — | WO | disclosed |