Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 4/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.38 |
| ▸ | CTSS | P25774 | 5/20 | 0.35 |
| ▸ | CTSL | P07711 | 2/20 | 0.35 |
| ▸ | PAK4 | O96013 | 2/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.32 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5806357 | 0.78 | FGFR4 (0.37) | CTSKOPRM1OPRL1CTSSCTSL | |
| SCHEMBL5808749 | 0.77 | CACNA1G (0.37) | CTSKCTSSCTSLPAK4MMP3 | |
| SCHEMBL5804565 | 0.76 | CTSK (0.42) | CTSKCTSSCTSLPAK4GPR119 | |
| SCHEMBL5792335 | 0.76 | CTSK (0.37) | CTSKOPRM1OPRL1CTSSCTSL | |
| Trifluoroacetic Acid SCHEMBL5808906 | 0.74 | HRH4 (0.34) | CTSKOPRM1OPRL1CTSSPAK4 | |
| SCHEMBL5792194 | 0.73 | CXCR3 (0.37) | KMT2AMEN1SMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL5791860 | 0.71 | CTSS (0.36) | CTSKCTSSPAK4MAPK8 | |
| SCHEMBL5791458 | 0.70 | KMT2A (0.41) | CTSKCTSSCTSLKMT2ATSHR | |
| SCHEMBL8270526 | 0.70 | CTSK (0.36) | CTSKOPRM1OPRL1CTSSCTSL | |
| SCHEMBL5794349 | 0.69 | CTSK (0.39) | CTSKCTSSCTSLFGFR4ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006027211-A1 | 2,4-SUBSTITUTED PYRIMIDINES AS CYSTEINE PROTEASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2006-03-16 | — | — | WO | disclosed |