Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 11/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 3/20 | 0.40 |
| ▸ | CA9 | Q16790 | 3/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL580501 | 0.79 | ALDH1A1 (0.74) | MCL1KDM4EAKR1B1ALDH1A1HPGD | |
| SCHEMBL13058664 | 0.77 | HSD17B3 (0.58) | MCL1KDM4EAKR1B1ALDH1A1HPGD | |
| SCHEMBL30350025 | 0.77 | MCL1 (0.76) | MCL1KDM4EAKR1B1ALDH1A1HPGD | |
| SCHEMBL7462235 | 0.77 | MCL1 (0.76) | MCL1KDM4EAKR1B1ALDH1A1HPGD | |
| SCHEMBL17553159 | 0.77 | MCL1 (0.57) | MCL1KDM4EAKR1B1ALDH1A1HPGD | |
| SCHEMBL7450481 | 0.76 | MCL1 (0.77) | MCL1KDM4EAKR1B1ALDH1A1HPGD | |
| SCHEMBL20602122 | 0.75 | MCL1 (0.44) | MCL1KDM4EAKR1B1ALDH1A1HPGD | |
| SCHEMBL31437397 | 0.73 | MCL1 (0.69) | MCL1KDM4EAKR1B1ALDH1A1HPGD | |
| SCHEMBL17768911 | 0.72 | GPR35 (0.62) | MCL1KDM4EAKR1B1ALDH1A1HPGD | |
| SCHEMBL14930073 | 0.72 | HSD17B3 (0.63) | MCL1KDM4EAKR1B1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021083459-A1 | PROCESS FOR THE SYNTHESIS OF DOPA COMPRISING A PHOTOLABILE PROTECTIVE GROUP, AND INTERMEDIATES FOR THE PREPARATION THEREOF | CHIRACON GMBH (DE) | 2021-05-06 | — | — | WO | claimed |
| EP-3316910-A1 | TRIPLET-TRIPLET ANNIHILATION-BASED UPCONVERSION | Children's Medical Center Corporation (US) | 2018-05-09 | — | — | EP | claimed |
| US-9714560-B2 | Protected scale inhibitors and methods relating thereto | HALLIBURTON ENERGY SERVICES, INC. (US) | 2017-07-25 | — | — | US | claimed |
| WO-2017004310-A1 | TRIPLET-TRIPLET ANNIHILATION-BASED UPCONVERSION | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2017-01-05 | — | — | WO | claimed |
| EP-2727915-B1 | Synthesis of deuterated catechols and benzo[d][1,3]dioxoles and derivatives thereof | CONCERT PHARMACEUTICALS INC (US) | 2016-04-13 | — | — | EP | claimed |
| US-8697109-B2 | Caged mercaptan and seleno-mercaptan compounds and methods of using them | ENCORE HEALTH, LLC (US) | 2014-04-15 | — | — | US | claimed |
| US-20110178281-A1 | Photocleavable Linker Methods and Compositions | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2011-07-21 | — | — | US | claimed |
| US-7923562-B2 | Photocleavable linker methods and compositions | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2011-04-12 | — | — | US | claimed |
| US-20100022761-A1 | PHOTOCLEAVABLE LINKER METHODS AND COMPOSITIONS | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2010-01-28 | — | — | US | claimed |
| US-20060008907-A1 | Control of gene expression via light activated RNA interference | THE CURATORS OF THE UNIVERSITY OF MISSOURI | 2006-01-12 | — | — | US | claimed |
| US-6703235-B2 | ADJUMENT OF SURFACE OF SOLID SUPPORT; OBTAIN SOLID SUPPORT, EXPOSE TO SENSITIZING AGENT AND LIGHT, MONITOR SURFACE | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2004-03-09 | — | — | US | claimed |
| US-20030013080-A1 | Complex multicellular assemblies ex vivo | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2003-01-16 | — | — | US | claimed |
| CN-117986153-A | Ionizable cationic lipid compound, and preparation method and application thereof | 晟迪生物医药(苏州)有限公司 | 2024-05-07 | — | — | CN | disclosed |
| US-11237156-B2 | Method and composition for detection of peptide cyclization using protein tags | Roche Sequencing Solutions, Inc. (US) | 2022-02-01 | — | — | US | disclosed |
| CN-107835871-B | Methods and compositions for peptide cyclization and protease treatment | 豪夫迈·罗氏有限公司 | 2021-07-02 | — | — | CN | disclosed |
| EP-3497446-B1 | METHOD AND COMPOSITION FOR DETECTION OF PEPTIDE CYCLIZATION USING PROTEIN TAGS | HOFFMANN LA ROCHE (CH) | 2021-04-28 | — | — | EP | disclosed |
| EP-1151350-A4 | PROTECTING GROUPS WITH INCREASED PHOTOSENSITIVITIES | UNIV CALIFORNIA (US) | 2002-08-21 | — | — | EP | disclosed |
| US-20020016472-A1 | PROTECTING GROUPS WITH INCREASED PHOTOSENSITIVITIES | REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE | 2002-02-07 | — | — | US | disclosed |
| EP-1151350-A1 | PROTECTING GROUPS WITH INCREASED PHOTOSENSITIVITIES | The Regents of the University of California (US) | 2001-11-07 | — | — | EP | disclosed |
| WO-2000031588-A1 | PROTECTING GROUPS WITH INCREASED PHOTOSENSITIVITIES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2000-06-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110178281-A1 | Photocleavable Linker Methods and Compositions | NSUN2, RNGTT, METTL16 | MCL1 1793/4885KDM4E 254/4885AKR1B1 2794/4885 |
| US-20100022761-A1 | PHOTOCLEAVABLE LINKER METHODS AND COMPOSITIONS | NSUN2, RNGTT, METTL16 | MCL1 1793/4885KDM4E 254/4885AKR1B1 2794/4885 |
| US-20020016472-A1 | PROTECTING GROUPS WITH INCREASED PHOTOSENSITIVITIES | ERCC4, XPA, GPX4 | MCL1 1400/4885KDM4E 4063/4885AKR1B1 2111/4885 |
| US-11237156-B2 | Method and composition for detection of peptide cyclization using protein tags | CACYBP, VIP, PTMS | MCL1 1502/4885KDM4E 4594/4885AKR1B1 2948/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.